NFYB anticorps (N-Term)

N° du produit ABIN2780750

Détail du produit anti-NFYB anticorps

Antigène: NFYB (Nuclear Transcription Factor Y, beta (NFYB))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFYB est non-conjugé

Application: Western Blotting (WB)

Séquence: MTMDGDSSTT DASQLGISAD YIGGSHYVIQ PHDDTEDSMN DHEDTNGSKE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against NFYB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NFYB

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 207 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-NFYB (ABIN2780750)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." dans: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Détails sur NFYB

Antigène: NFYB (Nuclear Transcription Factor Y, beta (NFYB))

Autre désignation: NFYB (NFYB Produits)

Synonymes: anticorps CBF-A, anticorps CBF-B, anticorps HAP3, anticorps NF-YB, anticorps NFYB, anticorps nfyb, anticorps zgc:110533, anticorps zgc:110552, anticorps hap3, anticorps cbf-a, anticorps cbf-b, anticorps CBFB, anticorps Nfya, anticorps AA985999, anticorps Cbf-A, anticorps nuclear transcription factor Y subunit beta, anticorps nuclear transcription factor Y subunit beta L homeolog, anticorps nuclear transcription factor Y, beta b, anticorps nuclear transcription factor Y, beta a, anticorps nuclear transcription factor-Y beta, anticorps NFYB, anticorps nfyb.L, anticorps nfybb, anticorps nfyba, anticorps nfyb, anticorps Nfyb

Sujet: NFYB is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence, protein sequence alignments and experiments with mutants.The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence, protein sequence alignments and experiments with mutants.
Alias Symbols: HAP3, CBF-A, CBF-B, NF-YB
Protein Interaction Partner: AGTRAP, POLE4, DRAP1, NFYA, LYN, CDK2, CCNE1, CCNA2, TP53, SMYD3, NFYC, MAOB, UBC, CREBBP, SP1, HDAC1, EP300, KAT2B, TP73, TAF12, TAF11, TAF6, GRB2, YBX3, CEBPZ, C1QBP, TBP, CIITA, CNTN2, MYC, ELF1, YBX1,
Protein Size: 207

Poids moléculaire: 23 kDa

ID gène: 4801

NCBI Accession: NM_006166, NP_006157

UniProt: P25208

Pathways: Regulation of Lipid Metabolism by PPARalpha