TADA3L anticorps (C-Term)
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- Antigène Voir toutes TADA3L (TADA3) Anticorps
- TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TADA3L est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- RVRMADNEVM DAFRKIMAAR QKKRTPTKKE KDQAWKTLKE RESILKLLDG
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against TADA3L. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human TADA3L
- Top Product
- Discover our top product TADA3 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 432 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))
- Autre désignation
- TADA3L (TADA3 Produits)
- Synonymes
- anticorps ADA3, anticorps NGG1, anticorps STAF54, anticorps TADA3L, anticorps hADA3, anticorps Tada3l, anticorps 1110004B19Rik, anticorps AI987856, anticorps fa03f04, anticorps tada3, anticorps wu:fa03f04, anticorps zgc:63596, anticorps ada3, anticorps ada3-A, anticorps ngg1, anticorps tada3l, anticorps tada3l-a, anticorps ada3-B, anticorps tada3l-B, anticorps transcriptional adaptor 3, anticorps transcriptional adapter 3 pseudogene, anticorps transcriptional adaptor 3 (NGG1 homolog, yeast)-like, anticorps transcriptional adaptor 3 L homeolog, anticorps transcriptional adaptor 3 S homeolog, anticorps TADA3, anticorps Tada3, anticorps LOC732883, anticorps LOC100061462, anticorps tada3, anticorps LOC100619707, anticorps tada3l, anticorps tada3.L, anticorps tada3.S
- Sujet
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Adaptor proteins are usually required for transcriptional activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter.TADA3L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.
Alias Symbols: ADA3, NGG1, hADA3, TADA3L
Protein Interaction Partner: HEXIM2, CCDC101, CCNC, TP53, USP22, KDM1A, TADA2A, KAT2B, TAF5L, NUP205, SUPT3H, YEATS2, MBIP, WDR5, MAP3K7, DR1, PIAS4, MAGEH1, ING5, XRCC6, SUMO2, SREBF1, TXNRD2, NR1I2, RARA, ESR1, AR, KAT2A, EP300, CTNNB1, ANKRD12, ATXN7, TAF10, FAM107B, ADPGK, HSPA8,
Protein Size: 432 - Poids moléculaire
- 49 kDa
- ID gène
- 10474
- NCBI Accession
- NM_006354, NP_006345
- UniProt
- O75528
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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