Coronin 1a anticorps (N-Term)
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- Antigène Voir toutes Coronin 1a (CORO1A) Anticorps
- Coronin 1a (CORO1A) (Coronin, Actin Binding Protein, 1A (CORO1A))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Coronin 1a est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MSRQVVRSSK FRHVFGQPAK ADQCYEDVRV SQTTWDSGFC AVNPKFVALI
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against CORO1A. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human CORO1A
- Top Product
- Discover our top product CORO1A Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 461 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Coronin 1a (CORO1A) (Coronin, Actin Binding Protein, 1A (CORO1A))
- Autre désignation
- CORO1A (CORO1A Produits)
- Synonymes
- anticorps CORO1A, anticorps cor1a, anticorps Clabp, anticorps Lmb3, anticorps TACO, anticorps p57, anticorps CLABP, anticorps CLIPINA, anticorps HCORO1, anticorps fj83g12, anticorps wu:fj83g12, anticorps zgc:63766, anticorps coronin 1A, anticorps Coronin-1A, anticorps coronin, actin binding protein 1A, anticorps coronin, actin binding protein, 1A, anticorps CORO1A, anticorps cor1a, anticorps Coro1a, anticorps coro1a
- Sujet
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CORO1A is a novel actin-binding protein with a WD repeat and a leucine zipper motif. CORO1A forms homodimers, that the association is mediated by the leucine zipper structure in the C-terminal region, and that it plays a role in the cross-linking of F-actin in the cell. The leukocyte plasma membrane associates with the actin cytoskeleton through CORO1A.Downregulation of CORO1A gene transcription restricts entry/survival of mycobacteria within macrophages
Alias Symbols: p57, TACO, CLABP, HCORO1, CLIPINA
Protein Interaction Partner: FSD2, GOLGA2, UBC, YTHDC1, SPATA20, POT1, TAB1, GIT2, POLR1C, STAT3, SMARCD1, MAGOH, SMAD3, LMO2, FHL3, FMNL1, NCF4, THBS1, ACTB, DKK1, UBE2G2,
Protein Size: 461 - Poids moléculaire
- 51 kDa
- ID gène
- 11151
- NCBI Accession
- NM_007074, NP_009005
- UniProt
- Q2YD73
- Pathways
- Regulation of Actin Filament Polymerization
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