MafF anticorps (N-Term)

N° du produit ABIN2780877

Détail du produit anti-MafF anticorps

Antigène: MafF (MAFF) (Transcription Factor MafF (MAFF))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MafF est non-conjugé

Application: Western Blotting (WB)

Séquence: SVRELNRHLR GLSAEEVTRL KQRRRTLKNR GYAASCRVKR VCQKEELQKQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MAFF. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MAFF

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 164 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MafF

Antigène: MafF (MAFF) (Transcription Factor MafF (MAFF))

Autre désignation: MAFF (MAFF Produits)

Synonymes: anticorps zgc:63868, anticorps MAFF, anticorps U-MAF, anticorps hMafF, anticorps MAF bZIP transcription factor F, anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F, anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F S homeolog, anticorps v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian), anticorps Maff, anticorps maff, anticorps MAFF, anticorps maff.S

Sujet: MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. MAFF can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. MAFF may also be involved in the cellular stress response.The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: U-MAF, hMafF
Protein Interaction Partner: NFE2L2, PARP1, BACH2, BATF3, MAFF, NFE2L3, NFIL3, NFE2L1, MAFG, FOS, DDIT3, BACH1, ATF3, BATF2, MAFIP, OVOL1, SUMO2, GTF2A1L, HDAC5, PPARG, NR3C1, NFE2, NRF1, PSAP, PRRX1, HOXD12,
Protein Size: 164

Poids moléculaire: 18 kDa

ID gène: 23764

NCBI Accession: NM_152878, NP_690617

UniProt: Q9ULX9

Pathways: Myometrial Relaxation and Contraction