NFAT1 anticorps (C-Term)
-
- Antigène Voir toutes NFAT1 Anticorps
- NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
-
Épitope
- C-Term
-
Reactivité
- Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Lapin, Poisson zèbre (Danio rerio)
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp NFAT1 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- PTVIQQQNAT SQRAAKNGPP VSDQKEVLPA GVTIKQEQNL DQTYLDDVNE
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
- Attributs du produit
- This is a rabbit polyclonal antibody against NFATC2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human NFATC2
- Top Product
- Discover our top product NFAT1 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 925 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
- Autre désignation
- NFATC2 (NFAT1 Produits)
- Synonymes
- anticorps NFATC2, anticorps AI607462, anticorps NF-ATc2, anticorps NFAT1, anticorps NFAT1-D, anticorps Nfatp, anticorps NFATP, anticorps nuclear factor of activated T-cells 2, anticorps nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2, anticorps NFATC2, anticorps nfatc2, anticorps Nfatc2
- Sujet
-
This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: NFAT1, NFATP
Protein Interaction Partner: GNB2, USP22, UBC, TNPO1, CSE1L, LRRK2, IQGAP1, PPP2R1A, JUN, NFATC2, CREBBP, IRF2BP2, TFAP4, HNRNPA1, TAF9, TUBA1A, KPNB1, SUV39H1, MAPK9, MAPK8, MED31, NFATC2IP, EP300, IRF4, PPP3R1, YWHAZ, PIN1, MEF2D, FOXP3, VIM, PRKCZ, YWHAQ, EGR4, EGR1, PPP3CB,
Protein Size: 925 - Poids moléculaire
- 100 kDa
- ID gène
- 4773
- NCBI Accession
- NM_173091, NP_775114
- UniProt
- Q13469
- Pathways
- Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, VEGF Signaling, BCR Signaling
-