NR2E3 anticorps (N-Term)
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- Antigène Voir toutes NR2E3 Anticorps
- NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NR2E3 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- METRPTALMS STVAAAAPAA GAASRKESPG RWGLGEDPTG VSPSLQCRVC
- Homologie
- Cow: 86%, Human: 100%, Mouse: 93%, Pig: 79%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against NR2E3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human NR2E3
- Top Product
- Discover our top product NR2E3 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 410 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Novel NR2E3 mutations (R104Q, R334G) associated with a mild form of enhanced S-cone syndrome demonstrate compound heterozygosity." dans: Ophthalmology, Vol. 112, Issue 12, pp. 2115, (2005) (PubMed).
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Novel NR2E3 mutations (R104Q, R334G) associated with a mild form of enhanced S-cone syndrome demonstrate compound heterozygosity." dans: Ophthalmology, Vol. 112, Issue 12, pp. 2115, (2005) (PubMed).
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- Antigène
- NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))
- Autre désignation
- NR2E3 (NR2E3 Produits)
- Synonymes
- anticorps ESCS, anticorps PNR, anticorps RNR, anticorps RP37, anticorps rd7, anticorps LOC100228348, anticorps A930035N01Rik, anticorps wu:fj55b07, anticorps zgc:103631, anticorps nuclear receptor subfamily 2 group E member 3, anticorps nuclear receptor subfamily 2, group E, member 3, anticorps NR2E3, anticorps Nr2e3, anticorps nr2e3
- Sujet
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NR2E3 is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. NR2E3 is a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome.This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: PNR, RNR, rd7, ESCS, RP37
Protein Interaction Partner: BCL11A, SIN3A, DHX30, TBL3, MYBBP1A, NCOR1, HDAC3, RBL1, RBBP7, RBBP4, HDAC1, CDK9, VDR, DEDD2, RBFOX2, IRF9, ZNF232, SNAPC1, PPARG, HOXC13, NR3C1, ELAVL2, POLR3D, RARA, NR1D1, CRX, RXRB, RXRA,
Protein Size: 410 - Poids moléculaire
- 45 kDa
- ID gène
- 10002
- NCBI Accession
- NM_014249, NP_055064
- UniProt
- Q9Y5X4
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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