BRD4 anticorps (C-Term)

N° du produit ABIN2780921

Détail du produit anti-BRD4 anticorps

Antigène: BRD4 (Bromodomain Containing 4 (BRD4))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRD4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)

Séquence: EIEIDFETLK PSTLRELERY VTSCLRKKRK PQAEKVDVIA GSSKMKGFSS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against BRD4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human BRD4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 722 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur BRD4

Antigène: BRD4 (Bromodomain Containing 4 (BRD4))

Autre désignation: BRD4 (BRD4 Produits)

Synonymes: anticorps brd4-b, anticorps BRD4, anticorps fb18g03, anticorps wu:fb18g03, anticorps CAP, anticorps HUNK1, anticorps HUNKI, anticorps MCAP, anticorps Brd5, anticorps WI-11513, anticorps bromodomain containing 4 L homeolog, anticorps bromodomain containing 4, anticorps bromodomain-containing protein 4, anticorps brd4.L, anticorps BRD4, anticorps brd4, anticorps LOC100409351, anticorps Brd4

Sujet: BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting.The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15,19)(q13,p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
Alias Symbols: CAP, HUNKI, MCAP, HUNK1
Protein Interaction Partner: AFF1, CDK9, CCNT1, STAT3, JMJD6, TCERG1, HEXIM1, RN7SK, PRPF40A, vif, RPL6, MYC, MLLT1, ELAVL1, SUMO2, UBC, YWHAZ, KAT8, C8orf33, MESDC2, HIST1H4A, HIST1H3A, YWHAE, MED1, EP300, KDM5B, C7orf25, CHFR, CLDN1, RFC1, RFC4, HIST2H3C, HIST2H4A, MED12, MED24, ME
Protein Size: 722

Poids moléculaire: 80 kDa

ID gène: 23476

NCBI Accession: NM_014299, NP_055114

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome