PRRX2 anticorps (N-Term)

N° du produit ABIN2781006

Détail du produit anti-PRRX2 anticorps

Antigène: PRRX2 (Paired Related Homeobox 2 (PRRX2))

Épitope: N-Term

Reactivité: Souris, Humain, Rat, Cheval, Porc, Boeuf (Vache), Chien, Lapin, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRRX2 est non-conjugé

Application: Western Blotting (WB)

Séquence: RKNFSVSHLL DLEEVAAAGR LAARPGARAE AREGAAREPS GGSSGSEAAP

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 79%, Rat: 79%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against PRRX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PRRX2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 253 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PRRX2 (ABIN2781006)

Tokutomi, Araki, Kataoka, Yamamoto, Kim-Mitsuyama: "Oxidation of Prx2 and phosphorylation of GRP58 by angiotensin II in human coronary smooth muscle cells identified by 2D-DIGE analysis." dans: Biochemical and biophysical research communications, Vol. 364, Issue 4, pp. 822-30, (2007) (PubMed).

Détails sur PRRX2

Antigène: PRRX2 (Paired Related Homeobox 2 (PRRX2))

Autre désignation: PRRX2 (PRRX2 Produits)

Synonymes: anticorps Prx2, anticorps PRRX2, anticorps PMX2, anticorps PRX2, anticorps S8, anticorps (S8), anticorps PRX-2, anticorps paired related homeobox 2, anticorps Prrx2, anticorps PRRX2

Sujet: PRRX2 is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.
Alias Symbols: MGC19843, PMX2, PRX2
Protein Interaction Partner: SOX10,
Protein Size: 253

Poids moléculaire: 27 kDa

ID gène: 51450

NCBI Accession: NM_016307, NP_057391

UniProt: Q99811