ZNF446 anticorps (C-Term)

N° du produit ABIN2781046

Détail du produit anti-ZNF446 anticorps

Antigène: ZNF446 (Zinc Finger Protein 446 (ZNF446))

Épitope: C-Term

Reactivité: Humain, Rat, Cobaye, Chien, Souris, Boeuf (Vache), Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF446 est non-conjugé

Application: Western Blotting (WB)

Séquence: SYPCEECGCS FSWKSQLVIH RKSHTGQRRH FCSDCGRAFD WKSQLVIHRK

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 75%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ZNF446. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ZNF446

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 450 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ZNF446

Antigène: ZNF446 (Zinc Finger Protein 446 (ZNF446))

Autre désignation: ZNF446 (ZNF446 Produits)

Synonymes: anticorps ZKSCAN20, anticorps ZSCAN30, anticorps ZSCAN52, anticorps AA120513, anticorps AV306632, anticorps A930031C22, anticorps A630035I11Rik, anticorps ZNF446, anticorps DKFZp468H2122, anticorps C230097I24Rik, anticorps Gm754, anticorps Zfp397os, anticorps zinc finger protein 446, anticorps zinc finger and SCAN domain containing 30, anticorps ZNF446, anticorps Zfp446, anticorps Znf446, anticorps Zscan30

Sujet: ZNF446 contains a KRAB and three C(2)H(2) zinc fingers. ZNF446 is a transcription repressor when fused to GAL4 DNA-binding domain and co-transfected with VP-16. Overexpression of ZNF446 in COS-7 cells inhibits the transcriptional activities of SRE and AP-1, suggesting that the ZNF446 protein may act as a transcriptional repressor in mitogen-activated protein kinase (MAPK) signaling pathway to mediate cellular functions.
Alias Symbols: ZSCAN30, ZKSCAN20
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, ZSCAN22, ZNF396, KRT40, ZNF496, PGBD1, LZTS2, ZNF397, ZSCAN16, ZKSCAN7, ZNF446, ZSCAN32, ZNF232, ZSCAN9, ZNF165, ZSCAN21, ZNF24, TRIM27, PIN1, DGCR6, ACTN2, FHL5, DGCR6L, SUFU, ZNF263,
Protein Size: 450

Poids moléculaire: 49 kDa

ID gène: 55663

NCBI Accession: NM_017908, NP_060378

UniProt: Q9NWS9