DMAP1 anticorps (N-Term)

N° du produit ABIN2781079

Détail du produit anti-DMAP1 anticorps

Antigène: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMAP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MATGADVRDI LELGGPEGDA ASGTISKKDI INPDKKKSKK SSETLTFKRP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against DMAP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DMAP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 467 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DMAP1

Antigène: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Autre désignation: DMAP1 (DMAP1 Produits)

Synonymes: anticorps Afu4g07380, anticorps T8I13.5, anticorps DNMAP1, anticorps DNMTAP1, anticorps EAF2, anticorps MEAF2, anticorps SWC4, anticorps zgc:55593, anticorps dnmap1, anticorps dnmtap1, anticorps eaf2, anticorps meaf2, anticorps swc4, anticorps 1500016M21Rik, anticorps Dmtap1, anticorps mKIAA1425, anticorps DNA methyltransferase 1-associated protein DMAP1, anticorps DNA methyltransferase 1-associated protein 1, anticorps DNA methyltransferase 1 associated protein 1, anticorps myb-like transcription factor family protein, anticorps DNA methyltransferase 1 associated protein 1 L homeolog, anticorps AFUA_4G07380, anticorps NFIA_108840, anticorps ACLA_046700, anticorps CpipJ_CPIJ017959, anticorps Bm1_47540, anticorps PMAA_026820, anticorps AFLA_112450, anticorps TSTA_072020, anticorps BDBG_02603, anticorps AT2G47210, anticorps CpipJ_CPIJ007438, anticorps DMAP1, anticorps dmap1, anticorps dmap1.L, anticorps Dmap1

Sujet: DMAP1 is a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.
Alias Symbols: EAF2, SWC4, MEAF2, DNMAP1, DNMTAP1
Protein Interaction Partner: SOX2, UBC, RNF2, HECW2, RUVBL2, SRCAP, CFDP1, RUVBL1, DENR, VPS72, TOMM34, TSG101, H2AFZ, DAXX, SMARCAD1, SUMO2, EPC1, ACTL6A, ACTA1, PPP2R2D, ING3, MORF4L1, BRD8, KAT5, TRRAP, YEATS4, EP400, EPC2, MYC, MAX, ACTG1, ACTB, MRGBP, MORF4L2, MNAT1, HDAC1, tat,
Protein Size: 467

Poids moléculaire: 53 kDa

ID gène: 55929

NCBI Accession: NM_019100, NP_061973

UniProt: Q9NPF5