MNT anticorps (N-Term)

N° du produit ABIN2781100

Détail du produit anti-MNT anticorps

Antigène: MNT (MNT, MAX Dimerization Protein (MNT))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cheval, Porc, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MNT est non-conjugé

Application: Western Blotting (WB)

Séquence: SIETLLEAAR FLEWQAQQQQ RAREEQERLR LEQEREQEQK KANSLARLAH

Homologie: Cow: 93%, Dog: 93%, Horse: 80%, Human: 100%, Mouse: 93%, Pig: 80%, Rabbit: 93%, Rat: 93%, Yeast: 92%

Attributs du produit: This is a rabbit polyclonal antibody against MNT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MNT

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 582 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MNT

Antigène: MNT (MNT, MAX Dimerization Protein (MNT))

Autre désignation: MNT (MNT Produits)

Synonymes: anticorps MAD6, anticorps MXD6, anticorps ROX, anticorps bHLHd3, anticorps etID309773.22, anticorps fb16b12, anticorps fb55f03, anticorps wu:fb16b12, anticorps wu:fb55f03, anticorps wu:fd06a08, anticorps wu:fz74f10, anticorps Rox, anticorps Mnt, anticorps zgc:165490, anticorps mnt, anticorps rox, anticorps MGC98824, anticorps MAX network transcriptional repressor, anticorps max interactor 1, dimerization protein, anticorps max binding protein, anticorps MAX network transcriptional repressor b, anticorps MAX network transcriptional repressor L homeolog, anticorps MNT, anticorps mxi1, anticorps Mnt, anticorps mntb, anticorps mnt.L

Sujet: The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. MNT is a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MAD6, MXD6, ROX, bHLHd3
Protein Interaction Partner: Dlg4, ELAVL1, CEBPA, MAX, MAD1L1, MYC, HDAC1, SIN3A, MNT, MLX, HMGB1,
Protein Size: 582

Poids moléculaire: 62 kDa

ID gène: 4335

NCBI Accession: NM_020310, NP_064706

UniProt: Q99583

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation