KDM6A anticorps (Middle Region)
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- Antigène Voir toutes KDM6A Anticorps
- KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KDM6A est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- KTYIVHCQDC ARKTSGNLEN FVVLEQYKME DLMQVYDQFT LAPPLPSASS
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against UTX. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human UTX
- Top Product
- Discover our top product KDM6A Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 1401 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))
- Autre désignation
- UTX (KDM6A Produits)
- Synonymes
- anticorps KABUK2, anticorps UTX, anticorps bA386N14.2, anticorps Utx, anticorps si:ch211-222m21.1, anticorps utx, anticorps kdm6a, anticorps tutx, anticorps uty, anticorps xtutx, anticorps lysine demethylase 6A, anticorps lysine-specific demethylase 6A, anticorps lysine (K)-specific demethylase 6A, anticorps lysine demethylase 6A S homeolog, anticorps KDM6A, anticorps LOC100539898, anticorps Kdm6a, anticorps kdm6a, anticorps kdm6a.S
- Sujet
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UTX is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitent with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
Alias Symbols: DKFZp686A03225, MGC141941, bA386N14.2, UTX, KABUK2
Protein Interaction Partner: KMT2D, WDR5, ASH2L, RBBP5, SMAD9, HIST2H3C, SRF, SMARCA4, GATA4, NKX2-5, TBX5, UBC, HIST1H3A, WDR82, PAXIP1, NCOA6, TLE1, PROSER1, KMT2C, N4BP2, PPP6R3, ZNF281, HIST3H3,
Protein Size: 1401 - Poids moléculaire
- 154 kDa
- ID gène
- 7403
- NCBI Accession
- NM_021140, NP_066963
- UniProt
- O15550
- Pathways
- Tube Formation, L'effet Warburg
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