PRDM12 anticorps (C-Term)

N° du produit ABIN2781154

Détail du produit anti-PRDM12 anticorps

Antigène: PRDM12 (PR Domain Containing 12 (PRDM12))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRDM12 est non-conjugé

Application: Western Blotting (WB)

Séquence: NHVRLHTGER PYKCQVCQSA YSQLAGLRAH QKSARHRPPS TALQAHSPAL

Homologie: Cow: 93%, Dog: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PRDM12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human PRDM12

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 367 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PRDM12

Antigène: PRDM12 (PR Domain Containing 12 (PRDM12))

Autre désignation: PRDM12 (PRDM12 Produits)

Synonymes: anticorps PRDM12, anticorps prdm12, anticorps MGC146714, anticorps PFM9, anticorps pfm9, anticorps Gm998, anticorps PR/SET domain 12, anticorps PR domain containing 12, anticorps PR domain containing 12 L homeolog, anticorps PR domain containing 12a, anticorps PRDM12, anticorps prdm12, anticorps prdm12.L, anticorps Prdm12, anticorps prdm12a

Sujet: PRDM12 belongs to PR-domain family which are involved in human cancers in an unusual yin-yang fashion. Two products are normally produced from a PR-domain family member which differ by the presence or absence of the PR domain, the PR-plus product is disrupted or underexpressed whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, a result of either genetic or epigenetic events, appears to be an important cause of malignancy. PRDM12 may have a potential role in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion.
Alias Symbols: PFM9
Protein Size: 367

Poids moléculaire: 40 kDa

ID gène: 59335

NCBI Accession: NM_021619, NP_067632

UniProt: Q9H4Q4