STEAP3 anticorps (C-Term)
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- Antigène Voir toutes STEAP3 Anticorps
- STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp STEAP3 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- VALVLSTLHT LTYGWTRAFE ESRYKFYLPP TFTLTLLVPC VVILAKALFL
- Homologie
- Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against STEAP3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human STEAP3
- Top Product
- Discover our top product STEAP3 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 498 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))
- Autre désignation
- STEAP3 (STEAP3 Produits)
- Synonymes
- anticorps STEAP3, anticorps 1010001D01Rik, anticorps Tsap6, anticorps pHyde, anticorps AHMIO2, anticorps STMP3, anticorps TSAP6, anticorps dudlin-2, anticorps STEAP3 metalloreductase, anticorps STEAP family member 3, anticorps STEAP3, anticorps steap3, anticorps Steap3
- Sujet
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AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+) and can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD(+) as acceptor (By similarity). It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT.
Alias Symbols: STMP3, TSAP6, dudlin-2
Protein Interaction Partner: UBC, SETD7, BAD, TPT1, BNIP3L, PKMYT1,
Protein Size: 498 - Poids moléculaire
- 56 kDa
- ID gène
- 55240
- NCBI Accession
- NM_182915, NP_878919
- UniProt
- A8K6E3
- Pathways
- Transition Metal Ion Homeostasis
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