ECH1 anticorps (N-Term)
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- Antigène Voir toutes ECH1 Anticorps
- ECH1 (Enoyl Coenzyme A Hydratase 1, Peroxisomal (ECH1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Cobaye, Lapin, Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ECH1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- PDHSYESLRV TSAQKHVLHV QLNRPNKRNA MNKVFWREMV ECFNKISRDA
- Homologie
- Cow: 100%, Dog: 92%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against ECH1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human ECH1
- Top Product
- Discover our top product ECH1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 328 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Ananas comosus L. Leaf Phenols and p-Coumaric Acid Regulate Liver Fat Metabolism by Upregulating CPT-1 Expression." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 903258, (2014) (PubMed).
: "Enhanced peroxisomal ?-oxidation metabolism in visceral adipose tissues of high-fat diet-fed obesity-resistant C57BL/6 mice." dans: Experimental and therapeutic medicine, Vol. 2, Issue 2, pp. 309-315, (2012) (PubMed).
: "
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Ananas comosus L. Leaf Phenols and p-Coumaric Acid Regulate Liver Fat Metabolism by Upregulating CPT-1 Expression." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 903258, (2014) (PubMed).
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- Antigène
- ECH1 (Enoyl Coenzyme A Hydratase 1, Peroxisomal (ECH1))
- Autre désignation
- ECH1 (ECH1 Produits)
- Synonymes
- anticorps HPXEL, anticorps Pxel, anticorps AA617331, anticorps enoyl-CoA hydratase 1, peroxisomal, anticorps enoyl CoA hydratase 1, peroxisomal, anticorps enoyl-CoA hydratase 1, anticorps delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial, anticorps enoyl-CoA hydratase 1, peroxisomal L homeolog, anticorps enoyl coenzyme A hydratase 1, peroxisomal, anticorps ech1, anticorps ECH1, anticorps LOC747511, anticorps ech1.L, anticorps Ech1
- Sujet
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ECH1 is a member of the hydratase/isomerase superfamily. ECH1 shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The protein contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway.This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.
Alias Symbols: HPXEL
Protein Interaction Partner: FAM9B, HUWE1, TRAF1, UBC, MDM2, PPP6R3, IQCB1, STAT3, PEX5, EEF1D, DNAJB11, HNRNPUL1, OPA1, APP, HTT, EEF1G, HDAC5, ICT1, TLR10, PAFAH1B3, SERPINB9, CSTF2, TIMP1,
Protein Size: 328 - Poids moléculaire
- 36 kDa
- ID gène
- 1891
- NCBI Accession
- NM_001398, NP_001389
- UniProt
- Q13011
- Pathways
- Monocarboxylic Acid Catabolic Process
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