SLC5A8 anticorps (Middle Region)
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- Antigène Voir toutes SLC5A8 Anticorps
- SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SLC5A8 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GILVPFANSI GALVGLMAGF AISLWVGIGA QIYPPLPERT LPLHLDIQGC
- Homologie
- Human: 100%, Mouse: 83%, Rabbit: 92%, Rat: 91%
- Attributs du produit
- This is a rabbit polyclonal antibody against SLC5A8. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human SLC5A8
- Top Product
- Discover our top product SLC5A8 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 610 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Molecular mechanism of SLC5A8 inactivation in breast cancer." dans: Molecular and cellular biology, Vol. 33, Issue 19, pp. 3920-35, (2013) (PubMed).
: "Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate." dans: Oncogene, Vol. 30, Issue 38, pp. 4026-37, (2011) (PubMed).
: "Activin A induces SLC5A8 expression through the Smad3 signaling pathway in human colon cancer RKO cells." dans: The international journal of biochemistry & cell biology, Vol. 42, Issue 12, pp. 1964-72, (2010) (PubMed).
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Molecular mechanism of SLC5A8 inactivation in breast cancer." dans: Molecular and cellular biology, Vol. 33, Issue 19, pp. 3920-35, (2013) (PubMed).
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- Antigène
- SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
- Autre désignation
- SLC5A8 (SLC5A8 Produits)
- Synonymes
- anticorps Ait, anticorps SMCT, anticorps SMCT1, anticorps AIT, anticorps RGD1564146, anticorps solute carrier family 5 (iodide transporter), member 8, anticorps solute carrier family 5 member 8, anticorps Slc5a8, anticorps SLC5A8
- Sujet
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SLC5A8 has been shown to transport iodide by a passive mechanism (Rodriguez et al., 2002 [PubMed 12107270]) and monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism (Gopal et al., 2004 [PubMed 15322102]). In kidney, SLC5A8 functions
Alias Symbols: AIT, MGC125354, SMCT, SMCT1
Protein Size: 610 - Poids moléculaire
- 66 kDa
- ID gène
- 160728
- NCBI Accession
- NM_145913, NP_666018
- UniProt
- Q8N695
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