SLC26A5 anticorps (Middle Region)

N° du produit ABIN2781751

Détail du produit anti-SLC26A5 anticorps

Antigène: SLC26A5 (Solute Carrier Family 26, Member 5 (Prestin) (SLC26A5))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC26A5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: FSVTISMAKT LANKHGYQVD GNQELIALGL CNSIGSLFQT FSISCSLSRS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SLC26A5. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SLC26A5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 744 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SLC26A5

Antigène: SLC26A5 (Solute Carrier Family 26, Member 5 (Prestin) (SLC26A5))

Autre désignation: SLC26A5 (SLC26A5 Produits)

Synonymes: anticorps pres, anticorps fb73d12, anticorps fb74g12, anticorps wu:fb73d12, anticorps wu:fb74g12, anticorps DFNB61, anticorps PRES, anticorps Pres, anticorps prestin, anticorps solute carrier family 26 (anion exchanger), member 5, anticorps solute carrier family 26 member 5, anticorps solute carrier family 26, member 5, anticorps slc26a5, anticorps SLC26A5, anticorps Slc26a5

Sujet: SLC26A5 is a member of the SLC26A/SulP transporter family. SLC26A5 is specifically expressed in outer hair cells (OHCs) of the cochlea and is essential in auditory processing. Intracellular anions are thought to act as extrinsic voltage sensors, which bind to this protein and trigger the conformational changes required for rapid length changes in OHCs. Mutations in its gene have been associated with non-syndromic hearing loss.This gene is a member of the SLC26A/SulP transporter family. It encodes a protein that is specifically expressed in outer hair cells (OHCs) of the cochlea and is essential in auditory processing. Intracellular anions are thought to act as extrinsic voltage sensors, which bind to this protein and trigger the conformational changes required for rapid length changes in OHCs. Mutations in this gene have been associated with non-syndromic hearing loss. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: DFNB61, MGC118886, MGC118887, MGC118888, MGC118889, PRES
Protein Size: 744

Poids moléculaire: 81 kDa

ID gène: 375611

NCBI Accession: NM_198999, NP_945350

UniProt: P58743

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport