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SGCB anticorps (Middle Region)

SGCB Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Cobaye, Cheval, Chien WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2781779
  • Antigène Voir toutes SGCB Anticorps
    SGCB (Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB))
    Épitope
    • 15
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 31
    • 26
    • 22
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Lapin, Boeuf (Vache), Cobaye, Cheval, Chien
    Hôte
    • 37
    • 4
    Lapin
    Clonalité
    • 37
    • 4
    Polyclonal
    Conjugué
    • 18
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SGCB est non-conjugé
    Application
    • 14
    • 13
    • 13
    • 11
    • 8
    • 6
    • 4
    • 4
    • 1
    Western Blotting (WB)
    Séquence
    FSTDYETHEF HLPSGVKSLN VQKASTERIT SNATSDLNIK VDGRAIVRGN
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against SGCB. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human SGCB
    Top Product
    Discover our top product SGCB Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 318 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    SGCB (Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB))
    Autre désignation
    SGCB (SGCB Produits)
    Synonymes
    anticorps A3b, anticorps LGMD2E, anticorps SGC, anticorps 43kDa, anticorps AI747103, anticorps AI844814, anticorps beta-SG, anticorps CG5657, anticorps DmSCG-beta, anticorps Dmel\\CG5657, anticorps dscgbeta, anticorps scg-beta, anticorps beta-sarcoglycan, anticorps fa03a05, anticorps wu:fa03a05, anticorps zgc:110833, anticorps sarcoglycan beta, anticorps sarcoglycan, beta (dystrophin-associated glycoprotein), anticorps Sarcoglycan beta, anticorps SarcoGlycaN, anticorps uncharacterized LOC5567384, anticorps beta-sarcoglycan, anticorps sarcoglycan, beta, anticorps sarcoglycan beta L homeolog, anticorps SGCB, anticorps Sgcb, anticorps Scgbeta, anticorps sgn-1, anticorps LOC5567384, anticorps CpipJ_CPIJ006944, anticorps sgcb.L, anticorps sgcb
    Sujet
    SGCB is a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix.The dystrophin-glycoprotein complex (DGC) is a multisubunit protein complex that spans the sarcolemma and provides structural linkage between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. There are 3 main subcomplexes of the DGC: the cytoplasmic proteins dystrophin (DMD, MIM 300377) and syntrophin (SNTA1, MIM 601017), the alpha- and beta-dystroglycans (see MIM 128239), and the sarcoglycans (see, e.g., SGCA, MIM 600119) (Crosbie et al., 2000 [PubMed 10942431]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1235 BC020709.1 1-1235 1236-1833 U31116.1 1257-1854 1834-4229 AK094731.1 47-2442
    Alias Symbols: A3b, LGMD2E, SGC
    Protein Interaction Partner: UBC, SGCZ, SGCG, SGCD, SGCA,
    Protein Size: 318
    Poids moléculaire
    35 kDa
    ID gène
    6443
    NCBI Accession
    NM_000232, NP_000223
    UniProt
    Q16585
    Pathways
    Myometrial Relaxation and Contraction, Maintenance of Protein Location
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