GGCX anticorps (Middle Region)

N° du produit ABIN2781826

Détail du produit anti-GGCX anticorps

Antigène: GGCX (gamma-Glutamyl Carboxylase (GGCX))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Mouton, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GGCX est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: FLLRKLYVFR RSFLMTCISL RNLILGRPSL EQLAQEVTYA NLRPFEAVGE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GGCX. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human GGCX

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 758 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GGCX

Antigène: GGCX (gamma-Glutamyl Carboxylase (GGCX))

Autre désignation: GGCX (GGCX Produits)

Synonymes: anticorps GGCX, anticorps cb751, anticorps si:ch1073-230p18.3, anticorps zgc:158736, anticorps ggcx, anticorps GGC, anticorps vkcfd1, anticorps CG13927, anticorps DgammaC, anticorps Dmel\\CG13927, anticorps dGC, anticorps dgammaC, anticorps gammaC, anticorps VKCFD1, anticorps gamma-glutamyl carboxylase, anticorps gamma-glutamyl carboxylase L homeolog, anticorps GGCX, anticorps ggcx, anticorps GC, anticorps sce5891, anticorps ggcx.L, anticorps Ggcx

Sujet: GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency.Gamma-glutamyl carboxylase accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP, MIM 112260) and bone matrix protein (MGP, MIM 154870).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ26629, VKCFD1
Protein Interaction Partner: UBC, DCP2, FBXO6, F9, F10, F7, F2, PROC, BGLAP,
Protein Size: 758

Poids moléculaire: 87 kDa

ID gène: 2677

NCBI Accession: NM_000821, NP_000812

UniProt: P38435

Pathways: SARS-CoV-2 Protein Interactome