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GGCX anticorps (Middle Region)

GGCX Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Mouton, Cobaye, Cheval WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2781826
  • Antigène Voir toutes GGCX Anticorps
    GGCX (gamma-Glutamyl Carboxylase (GGCX))
    Épitope
    • 15
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 34
    • 21
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Mouton, Cobaye, Cheval
    Hôte
    • 47
    • 1
    • 1
    Lapin
    Clonalité
    • 49
    Polyclonal
    Conjugué
    • 14
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GGCX est non-conjugé
    Application
    • 25
    • 23
    • 18
    • 13
    • 13
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    FLLRKLYVFR RSFLMTCISL RNLILGRPSL EQLAQEVTYA NLRPFEAVGE
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against GGCX. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human GGCX
    Top Product
    Discover our top product GGCX Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 758 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    GGCX (gamma-Glutamyl Carboxylase (GGCX))
    Autre désignation
    GGCX (GGCX Produits)
    Synonymes
    anticorps GGCX, anticorps cb751, anticorps si:ch1073-230p18.3, anticorps zgc:158736, anticorps ggcx, anticorps GGC, anticorps vkcfd1, anticorps CG13927, anticorps DgammaC, anticorps Dmel\\CG13927, anticorps dGC, anticorps dgammaC, anticorps gammaC, anticorps VKCFD1, anticorps gamma-glutamyl carboxylase, anticorps gamma-glutamyl carboxylase L homeolog, anticorps GGCX, anticorps ggcx, anticorps GC, anticorps sce5891, anticorps ggcx.L, anticorps Ggcx
    Sujet
    GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency.Gamma-glutamyl carboxylase accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP, MIM 112260) and bone matrix protein (MGP, MIM 154870).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: FLJ26629, VKCFD1
    Protein Interaction Partner: UBC, DCP2, FBXO6, F9, F10, F7, F2, PROC, BGLAP,
    Protein Size: 758
    Poids moléculaire
    87 kDa
    ID gène
    2677
    NCBI Accession
    NM_000821, NP_000812
    UniProt
    P38435
    Pathways
    SARS-CoV-2 Protein Interactome
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