LCLAT1 anticorps (Middle Region)

N° du produit ABIN2781857

Détail du produit anti-LCLAT1 anticorps

Antigène: LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))

Épitope: Middle Region

Reactivité: Souris, Humain, Rat, Lapin, Cheval, Boeuf (Vache), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LCLAT1 est non-conjugé

Application: Western Blotting (WB)

Séquence: YLYSLVKWYF IITIVIFVLQ ERIFGGLEII ELACYRLLHK QPHLNSKKNE

Homologie: Cow: 93%, Dog: 92%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against LYCAT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human LYCAT

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 376 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-LCLAT1 (ABIN2781857)

Zou, Synan, Li, Xiong, Manni, Liu, Chen, Zhao, Shiva, Tyurina, Jiang, Lee, Das, Ray, Ray, Kagan, Mallampalli: "LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1." dans: Journal of cell science, Vol. 129, Issue 1, pp. 51-64, (2016) (PubMed).

Détails sur LCLAT1

Antigène: LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))

Autre désignation: LYCAT (LCLAT1 Produits)

Synonymes: anticorps lclat1, anticorps zgc:77380, anticorps wu:fj17g04, anticorps LYCAT, anticorps lycat, anticorps agpat8, anticorps alcat1, anticorps 1agpat8, anticorps AGPATP8, anticorps 1AGPAT8, anticorps AGPAT8, anticorps ALCAT1, anticorps HSRG1849, anticorps UNQ1849, anticorps AI181996, anticorps Agpat8, anticorps Alcat1, anticorps Gm91, anticorps Lycat, anticorps RGD1565906, anticorps lysocardiolipin acyltransferase 1, anticorps lclat1, anticorps LCLAT1, anticorps Lclat1

Sujet: LYCAT is an acyl-CoA:lysocardiolipin acyltransferase. It possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. LYCAT recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. LYCAT acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. It converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. LYCAT is required for establishment of the hematopoietic and endothelial lineages.
Alias Symbols: ALCAT1, FLJ37965, UNQ1849, LYCAT, AGPAT8, 1AGPAT8, HSRG1849
Protein Interaction Partner: LNX1, GOPC, RNF2, UBC, ELAVL1,
Protein Size: 376

Poids moléculaire: 44 kDa

ID gène: 253558

NCBI Accession: NM_001002257, NP_001002257

UniProt: Q6UWP7