Derlin-3 anticorps (C-Term)

N° du produit ABIN2781869

Détail du produit anti-Derlin-3 anticorps

Antigène: Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Cobaye, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Derlin-3 est non-conjugé

Application: Western Blotting (WB)

Séquence: YYFLEDVFPN QPGGKRLLQT PGFLKLLLDA PAEDPNYLPL PEEQPGPHLP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against DERL3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human DERL3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 235 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Derlin-3

Antigène: Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))

Autre désignation: DERL3 (DERL3 Produits)

Synonymes: anticorps 1810006I20Rik, anticorps 1810063P04Rik, anticorps IZP6, anticorps derlin-3, anticorps zgc:63991, anticorps C22orf14, anticorps LLN2, anticorps derlin 3, anticorps Der1-like domain family, member 3, anticorps DERL3, anticorps Derl3, anticorps derl3

Sujet: DERL3 belongs to the derlin family, and resides in the endoplasmic reticulum (ER). Proteins that are unfolded or misfolded in the ER must be refolded or degraded to maintain the homeostasis of the ER. This protein appears to be involved in the degradation of misfolded glycoproteins in the ER. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL3 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 [PubMed 16449189]).[supplied by OMIM].
Alias Symbols: C22orf14, IZP6, MGC71803, LLN2, derlin-3
Protein Interaction Partner: ERN1, UBE2J1, SERPINA1, MFI2, AMFR,
Protein Size: 235

Poids moléculaire: 27 kDa

ID gène: 91319

NCBI Accession: NM_001002862, NP_001002862

UniProt: Q96Q80

Pathways: ER-Nucleus Signaling