Ectodysplasin A anticorps (Middle Region)

N° du produit ABIN2781905

Détail du produit anti-Ectodysplasin A anticorps

Antigène: Ectodysplasin A (EDA)

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chévre, Cobaye, Cheval, Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ectodysplasin A est non-conjugé

Application: Western Blotting (WB)

Séquence: HLQGQGSAIQ VKNDLSGGVL NDWSRITMNP KVFKLHPRSG ELEVLVDGTY

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against EDA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human EDA

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 389 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Ectodysplasin A (ABIN2781905)

Zhao, Watt, Battle, Li, Bondow, Duncan: "Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice." dans: Developmental biology, Vol. 317, Issue 2, pp. 614-9, (2008) (PubMed).

Détails sur Ectodysplasin A

Antigène: Ectodysplasin A (EDA)

Autre désignation: EDA (EDA Produits)

Synonymes: anticorps ECTD1, anticorps ED1, anticorps ED1-A1, anticorps ED1-A2, anticorps EDA-A1, anticorps EDA-A2, anticorps EDA1, anticorps EDA2, anticorps HED, anticorps HED1, anticorps ODT1, anticorps STHAGX1, anticorps XHED, anticorps XLHED, anticorps si:ch73-223d24.5, anticorps Ed1, anticorps Eda-A1, anticorps Eda-A2, anticorps Ta, anticorps tabby, anticorps RGD1563178, anticorps ectodysplasin A, anticorps ectodysplasin-A, anticorps EDA, anticorps eda, anticorps Eda

Sujet: EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. It belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.
Alias Symbols: ED1, ED1-A1, ED1-A2, EDA1, EDA2, HED, XHED, XLHED, ODT1, STHAGX1
Protein Interaction Partner: OSTCP1, OSTC, NIPAL3, GIMAP5, SEC22A, LEPROTL1, DOLK, PLN, MAL, EMP3, CYB561, ATP6V0C, EDAR, EDA, EDA2R, FURIN,
Protein Size: 389

Poids moléculaire: 41 kDa

ID gène: 1896

NCBI Accession: NM_001005609, NP_001005609

UniProt: B7ZLU4

Pathways: Tube Formation