ACVR1 anticorps (N-Term)
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- Antigène Voir toutes ACVR1 (ACRV1) Anticorps
- ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Chévre, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ACVR1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- TCKTPPSPGQ AVECCQGDWC NRNITAQLPT KGKSFPGTQN FHLEVGLIIL
- Homologie
- Cow: 100%, Dog: 93%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against ACVR1. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human ACVR1
- Top Product
- Discover our top product ACRV1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 509 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))
- Autre désignation
- ACVR1 (ACRV1 Produits)
- Synonymes
- anticorps ACTRI, anticorps ACVR1A, anticorps ACVRLK2, anticorps ALK2, anticorps FOP, anticorps SKR1, anticorps TSRI, anticorps ActR-IA, anticorps ActR-I, anticorps ActRIA, anticorps Acvr, anticorps Acvrlk2, anticorps Alk-2, anticorps Alk8, anticorps D330013D15Rik, anticorps Tsk7L, anticorps actri, anticorps acvr1, anticorps acvr1-a, anticorps acvr1-b, anticorps acvr1a, anticorps acvrlk2, anticorps alk-2, anticorps alk2, anticorps alk8, anticorps fop, anticorps sax, anticorps skr1, anticorps tsri, anticorps xALK-2, anticorps activin A receptor type 1, anticorps activin A receptor, type 1, anticorps activin A receptor type 1 S homeolog, anticorps ACVR1, anticorps Acvr1, anticorps acvr1.S
- Sujet
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Activin receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. ACVR1 is activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors.Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors.
Alias Symbols: ACTRI, ACVRLK2, ALK2, FOP, SKR1, TSRI, ACVR1A
Protein Interaction Partner: UBC, USP15, BMPR1A, ACVR1, INHBA, ACVR2A, PEG10, SMAD6, SMAD7, BAMBI, SMURF1, IGSF1, TSC22D1, TGFBR1, DCAF6, FGD6, FCHO1, PLEK, TTC17, RHEBL1, WDR61, RASL12, RASD2, PLEKHJ1, CDK14, NEK8, DUSP13, NUAK2, FKBP4, RAB6B, RAB17, UBXN1, FBXO30, RHOJ, PLEKHB1, UB
Protein Size: 509 - Poids moléculaire
- 55 kDa
- ID gène
- 90
- NCBI Accession
- NM_001105, NP_001096
- UniProt
- Q04771
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