ACVR2B anticorps (Middle Region)
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- Antigène Voir toutes ACVR2B Anticorps
- ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Mouton, Poisson zèbre (Danio rerio), Lapin, Chévre
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ACVR2B est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- KSKNVLLKSD LTAVLADFGL AVRFEPGKPP GDTHGQVGTR RYMAPEVLEG
- Homologie
- Cow: 100%, Dog: 100%, Goat: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against ACVR2B. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human ACVR2B
- Top Product
- Discover our top product ACVR2B Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 512 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
- Autre désignation
- ACVR2B (ACVR2B Produits)
- Synonymes
- anticorps ACVR2B, anticorps XAR1, anticorps actr-iib, anticorps actriib, anticorps ACTRIIB, anticorps ActR-IIB, anticorps HTX4, anticorps ActRIIB, anticorps actr2b, anticorps actrIIb, anticorps wu:fj97d11, anticorps activin A receptor type 2B, anticorps activin A receptor type 2B L homeolog, anticorps activin A receptor type 2Ba, anticorps activin receptor IIB, anticorps ACVR2B, anticorps acvr2b, anticorps acvr2b.L, anticorps Acvr2b, anticorps acvr2ba
- Sujet
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Activin receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. ACVR2B is activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.
Alias Symbols: ACTRIIB, ActR-IIB, MGC116908, HTX4
Protein Interaction Partner: GDF2, BMP10, INHBA, PEG10, ERBB2IP, HSP90AA1, SMAD7, SMAD6, SMAD2, IGSF1, SYNJ2BP, SNX6, SNX2, TGFBRAP1, GDF11, MSTN, ACVR1B, SNX1, INHBC, GDF5, INHBB, BMP7, BMP2, ENG, BMP6,
Protein Size: 512 - Poids moléculaire
- 58 kDa
- ID gène
- 93
- NCBI Accession
- NM_001106, NP_001097
- UniProt
- Q13705
- Pathways
- Hormone Transport, Cancer Immune Checkpoints
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