AOC2 anticorps (Middle Region)

N° du produit ABIN2782115

Détail du produit anti-AOC2 anticorps

Antigène: AOC2 (Amine Oxidase, Copper Containing 2 (Retina-Specific) (AOC2))

Épitope: Middle Region

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Lapin, Cheval, Rat, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AOC2 est non-conjugé

Application: Western Blotting (WB)

Séquence: AEDIPNTVTL GNRVGFLLRP YNFFDEDPSI FSPGSVYFEK GQDAGLCSIN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 82%

Attributs du produit: This is a rabbit polyclonal antibody against AOC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human AOC2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 756 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur AOC2

Antigène: AOC2 (Amine Oxidase, Copper Containing 2 (Retina-Specific) (AOC2))

Autre désignation: AOC2 (AOC2 Produits)

Synonymes: anticorps DAO2, anticorps RAO, anticorps AOC2, anticorps AOC3, anticorps aoc3, anticorps wu:fa94a08, anticorps wu:fe14c05, anticorps zgc:113006, anticorps amine oxidase, copper containing 2, anticorps amine oxidase, copper containing 2 (retina-specific), anticorps membrane primary amine oxidase-like, anticorps retina-specific copper amine oxidase, anticorps AOC2, anticorps Aoc2, anticorps LOC100353051, anticorps aoc2

Sujet: Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants.
Alias Symbols: DAO2, RAO
Protein Size: 756

Poids moléculaire: 84 kDa

ID gène: 314

NCBI Accession: NM_009590, NP_033720

UniProt: O75106