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IL12RB2 anticorps (Middle Region)
IL12RB2
Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Cobaye, Cheval, Lapin, Mouton
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN2782132
Détail du produit anti-IL12RB2 anticorps
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Antigène
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IL12RB2
(Interleukin 12 Receptor, beta 2 (IL12RB2))
Épitope
Tous les épitopes à travers IL12RB2 Anticorps.
Middle Region
Reactivité
Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Cobaye, Cheval, Lapin, Mouton
Hôte
Toutes les hôtes sur IL12RB2 Anticorps
Lapin
Clonalité
Toutes les clonalités sur IL12RB2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers IL12RB2 Anticorps
Cet anticorp IL12RB2 est non-conjugé
Application
Tous les applications à travers IL12RB2 Anticorps.
Western Blotting (WB)
Séquence
DVWYMKRHID YSRQQISLFW KNLSVSEARG KILHYQVTLQ ELTGGKAMTQ
Homologie
Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%, Sheep: 100%
Attributs du produit
This is a rabbit polyclonal antibody against IL12RB2. It was validated on Western Blot.
Purification
Affinity Purified
Immunogène
The immunogen is a synthetic peptide directed towards the middle region of Human IL12RB2
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeat freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Détails sur IL12RB2
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Antigène
IL12RB2
(Interleukin 12 Receptor, beta 2 (IL12RB2))
Autre désignation
IL12RB2 (IL12RB2 Produits )
Synonymes
anticorps IL12RB2, anticorps A930027I18Rik, anticorps IL-12RB2, anticorps Ifnm, anticorps interleukin 12 receptor subunit beta 2, anticorps interleukin 12 receptor, beta 2, anticorps IL12RB2, anticorps Il12rb2
Sujet
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Protein Interaction Partner: SOCS3, IL12RB2, IL12RB1, STAT4, IL12B, JAK2, Protein Size: 659
Poids moléculaire
72 kDa
ID gène
3595
Pathways
Signalistation JAK/STAT
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