Cadherin 4 anticorps (Middle Region)

N° du produit ABIN2782140

Détail du produit anti-Cadherin 4 anticorps

Antigène: Cadherin 4 (CDH4)

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 4 est non-conjugé

Application: Western Blotting (WB)

Séquence: RIISGDPSGH FSVRTDPVTN EGMVTVVKAV DYELNRAFML TVMVSNQAPL

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 77%

Attributs du produit: This is a rabbit polyclonal antibody against CDH4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CDH4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 916 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Cadherin 4

Antigène: Cadherin 4 (CDH4)

Autre désignation: CDH4 (CDH4 Produits)

Synonymes: anticorps cad4, anticorps rcad, anticorps R-cadherin, anticorps cadherin-4, anticorps AW120700, anticorps R-Cadh, anticorps Rcad, anticorps Cdh4l, anticorps zgc:136316, anticorps CAD4, anticorps RCAD, anticorps cadherin 4, anticorps cadherin 4, type 1, R-cadherin (retinal), anticorps Cadherin-4, anticorps cdh4, anticorps Cdh4, anticorps CDH4, anticorps cdh-4

Sujet: CDH4 gene is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.
Alias Symbols: CAD4, FLJ22202, FLJ40547, MGC126700, MGC138355, RCAD
Protein Interaction Partner: FUS, Dlg4, CDK5RAP3, CDH2,
Protein Size: 916

Poids moléculaire: 82 kDa

ID gène: 1002

NCBI Accession: NM_001794, NP_001785

UniProt: P55283

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size