PTPRN anticorps (Middle Region)
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- Antigène Voir toutes PTPRN Anticorps
- PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
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Épitope
- Middle Region
- Reactivité
- Humain, Rat, Souris, Boeuf (Vache), Porc, Cobaye, Lapin, Chien, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PTPRN est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- EVQQVPSPVS SEPPKAARPP VTPVLLEKKS PLGQSQPTVA GQPSARPAAE
- Homologie
- Cow: 86%, Dog: 100%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against PTPRN. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human PTPRN
- Top Product
- Discover our top product PTPRN Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 591 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
- Autre désignation
- PTPRN (PTPRN Produits)
- Synonymes
- anticorps IA-2, anticorps IA-2/PTP, anticorps IA2, anticorps ICA512, anticorps R-PTP-N, anticorps mIA-A, anticorps mKIAA4064, anticorps Ia-2, anticorps fc43c04, anticorps ptprn, anticorps wu:fc43c04, anticorps ia-2, anticorps ia2, anticorps ica512, anticorps r-ptp-n, anticorps protein tyrosine phosphatase, receptor type N, anticorps protein tyrosine phosphatase, receptor type, N, anticorps protein tyrosine phosphatase, receptor type, Na, anticorps protein tyrosine phosphatase, receptor type N L homeolog, anticorps PTPRN, anticorps Ptprn, anticorps ptprna, anticorps ptprn.L
- Sujet
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PTPRN is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.
Alias Symbols: FLJ16131, IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
Protein Interaction Partner: PLP1, MAL, CLN8, UBQLN4, SNX19, SPTBN4, PTPRT, MADD, PTPRS, SNTB2, NOS1, PPIA, CAPN2,
Protein Size: 889 - Poids moléculaire
- 96 kDa
- ID gène
- 5798
- NCBI Accession
- NM_001199763
- UniProt
- Q16849
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