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TAPBP anticorps (N-Term)

TAPBP Reactivité: Humain, Souris, Rat, Mouton, Porc, Cheval, Chien, Lapin WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2782217
  • Antigène Voir toutes TAPBP Anticorps
    TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
    Épitope
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Souris, Rat, Mouton, Porc, Cheval, Chien, Lapin
    Hôte
    • 36
    Lapin
    Clonalité
    • 36
    Polyclonal
    Conjugué
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TAPBP est non-conjugé
    Application
    • 29
    • 14
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    GKGLAKRPGA LLLRQGPGEP PPRPDLDPEL YLSVHDPAGA LQAAFRRYPR
    Homologie
    Dog: 93%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 93%, Rat: 86%, Sheep: 79%
    Attributs du produit
    This is a rabbit polyclonal antibody against TAPBP. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human TAPBP
    Top Product
    Discover our top product TAPBP Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 299 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
    Autre désignation
    TAPBP (TAPBP Produits)
    Synonymes
    anticorps SI:dZ179B20.1, anticorps SI:dZ179B20.3, anticorps SI:dZ179B20.7, anticorps mhc1uda, anticorps mhc1ufa, anticorps tpsn, anticorps zgc:109814, anticorps tapbp, anticorps TAPBP, anticorps D17Wsu91e, anticorps TPN, anticorps NGS17, anticorps TAPA, anticorps TPSN, anticorps TAP binding protein (tapasin), tandem duplicate 1, anticorps TAP binding protein, anticorps tapbp.1, anticorps tapbp, anticorps TAPBP, anticorps Tapbp
    Sujet
    TAPBP is a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum.
    Alias Symbols: NGS17, TAPA, TPN, TPSN
    Protein Interaction Partner: UBC, PDIA3, Tap2, ELAVL1, US3, TAP1, B2M, COPG1, COPG2, COPB1, HLA-C, HLA-A, CALR,
    Protein Size: 299
    Poids moléculaire
    30 kDa
    ID gène
    6892
    NCBI Accession
    NM_172208, NP_757345
    UniProt
    O15533
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