TAPBP anticorps (C-Term)

N° du produit ABIN2782218

Détail du produit anti-TAPBP anticorps

Antigène: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Épitope: C-Term

Reactivité: Humain, Mouton, Boeuf (Vache), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAPBP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: GEAPPELLCL VSHFYPSGGL EVEWELRGGP GGRSQKAEGQ RWLSALRHHS

Homologie: Cow: 86%, Human: 100%, Pig: 86%, Sheep: 86%

Attributs du produit: This is a rabbit polyclonal antibody against TAPBP. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human TAPBP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 448 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TAPBP

Antigène: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Autre désignation: TAPBP (TAPBP Produits)

Synonymes: anticorps SI:dZ179B20.1, anticorps SI:dZ179B20.3, anticorps SI:dZ179B20.7, anticorps mhc1uda, anticorps mhc1ufa, anticorps tpsn, anticorps zgc:109814, anticorps tapbp, anticorps TAPBP, anticorps D17Wsu91e, anticorps TPN, anticorps NGS17, anticorps TAPA, anticorps TPSN, anticorps TAP binding protein (tapasin), tandem duplicate 1, anticorps TAP binding protein, anticorps tapbp.1, anticorps tapbp, anticorps TAPBP, anticorps Tapbp

Sujet: TAPBP is a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum.This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
Alias Symbols: NGS17, TAPA, TPN, TPSN
Protein Interaction Partner: UBC, PDIA3, Tap2, ELAVL1, US3, TAP1, B2M, COPG1, COPG2, COPB1, HLA-C, HLA-A, CALR,
Protein Size: 448

Poids moléculaire: 46 kDa

ID gène: 6892

NCBI Accession: NM_003190, NP_003181

UniProt: O15533