TGFB2 anticorps (Middle Region)
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- Antigène Voir toutes TGFB2 Anticorps
- TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cheval, Lapin, Mouton, Cobaye, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TGFB2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- NLVKAEFRVF RLQNPKARVP EQRIELYQIL KSKDLTSPTQ RYIDSKVVKT
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against TGFB2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human TGFB2
- Top Product
- Discover our top product TGFB2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 414 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
- Autre désignation
- TGFB2 (TGFB2 Produits)
- Synonymes
- anticorps LDS4, anticorps TGF-beta2, anticorps tgf-beta2, anticorps tgfb2-A, anticorps BB105277, anticorps Tgf-beta2, anticorps Tgfb-2, anticorps TGF-beta 2, anticorps Tgfbr2T, anticorps TGFB2, anticorps TGFbeta2, anticorps MGF, anticorps TGF-B2, anticorps transforming growth factor beta 2, anticorps transforming growth factor beta 2 L homeolog, anticorps transforming growth factor, beta 2, anticorps transforming growth factor, beta receptor 2, anticorps TGFB2, anticorps tgfb2.L, anticorps Tgfb2, anticorps Tgfbr2, anticorps tgfb2
- Sujet
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This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1,7)(q41,p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: MGC116892, TGF-beta2
Protein Interaction Partner: CEBPA, UBC, VASN, PZP, LTBP3, TGFBR3, FMOD, VTN, TGFB3, TGFB2, TGFBR2, TGFBR1, TGFB1, ENG, CTGF, BMP2, APP, TGFBRAP1, DAXX, DCN,
Protein Size: 414 - Poids moléculaire
- 46 kDa
- ID gène
- 7042
- NCBI Accession
- NM_003238, NP_003229
- UniProt
- P61812
- Pathways
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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