DEGS1 anticorps (N-Term)

N° du produit ABIN2782243

Détail du produit anti-DEGS1 anticorps

Antigène: DEGS1 (Sphingolipid Delta(4)-Desaturase DES1 (DEGS1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chévre, Cheval, Lapin, Mouton, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DEGS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: GSRVSREDFE WVYTDQPHAD RRREILAKYP EIKSLMKPDP NLIWIIIMMV

Homologie: Cow: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against DEGS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DEGS1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 323 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DEGS1

Antigène: DEGS1 (Sphingolipid Delta(4)-Desaturase DES1 (DEGS1))

Autre désignation: DEGS1 (DEGS1 Produits)

Synonymes: anticorps DEGS, anticorps DEGS-1, anticorps DES1, anticorps Des-1, anticorps FADS7, anticorps MLD, anticorps degs, anticorps im:6909319, anticorps wu:fa25h01, anticorps wu:fb81d06, anticorps Degs, anticorps AA536663, anticorps Des1, anticorps Mdes, anticorps delta 4-desaturase, sphingolipid 1, anticorps delta(4)-desaturase, sphingolipid 1, anticorps DEGS1, anticorps degs1, anticorps Degs1

Sujet: DEGS1 is a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this protein inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified.
Alias Symbols: DEGS, DES1, Des-1, FADS7, MGC5079, MIG15, MLD, DEGS-1
Protein Interaction Partner: UBC, NAGPA, UBD, EGFR, TSSC1, SURF4, SLC16A1, PYGM,
Protein Size: 323

Poids moléculaire: 38 kDa

ID gène: 8560

NCBI Accession: NM_003676, NP_003667

UniProt: O15121