IGFBP4 anticorps (Middle Region)

N° du produit ABIN2782316

Détail du produit anti-IGFBP4 anticorps

Antigène: IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Mouton, Chévre, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IGFBP4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: RALERLAASQ SRTHEDLYII PIPNCDRNGN FHPKQCHPAL DGQRGKCWCV

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against IGFBP4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human IGFBP4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 258 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-IGFBP4 (ABIN2782316)

Shi, Chiang, Mistretta, Major, Mori-Akiyama: "SOX9 directly regulates IGFBP-4 in the intestinal epithelium." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 305, Issue 1, pp. G74-83, (2013) (PubMed).

Détails sur IGFBP4

Antigène: IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))

Autre désignation: IGFBP4 (IGFBP4 Produits)

Synonymes: anticorps IGFBP4, anticorps igfbp4, anticorps BP-4, anticorps HT29-IGFBP, anticorps IBP4, anticorps IGFBP-4, anticorps AI875747, anticorps Deb2, anticorps IGF-BP4, anticorps IBP-4, anticorps insulin like growth factor binding protein 4, anticorps insulin-like growth factor-binding protein 4, anticorps insulin-like growth factor binding protein 4, anticorps IGFBP4, anticorps LOC100136305, anticorps LOC100194498, anticorps igfbp4, anticorps Igfbp4

Sujet: IGFBP4 is a member of the insulin-like growth factor binding protein (IGFBP) family. IGFBP4 is a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BP-4, HT29-IGFBP, IBP4, IGFBP-4
Protein Interaction Partner: KDM1A, SUV39H1, Hk3, Hk2, TF, PAPPA, IGF2, IGF1, CTSD,
Protein Size: 258

Poids moléculaire: 28 kDa

ID gène: 3487

NCBI Accession: NM_001552, NP_001543

UniProt: P22692

Pathways: Signalisation WNT, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process