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CBS anticorps (N-Term)

CBS Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2782348
  • Antigène Voir toutes CBS Anticorps
    CBS (Cystathionine-beta-Synthase (CBS))
    Épitope
    • 15
    • 9
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 54
    • 40
    • 11
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)
    Hôte
    • 65
    • 9
    Lapin
    Clonalité
    • 59
    • 15
    Polyclonal
    Conjugué
    • 39
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CBS est non-conjugé
    Application
    • 56
    • 31
    • 16
    • 15
    • 14
    • 14
    • 13
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    RCIIVMPEKM SSEKVDVLRA LGAEIVRTPT NARFDSPESH VGVAWRLKNE
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 93%
    Attributs du produit
    This is a rabbit polyclonal antibody against CBS. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human CBS
    Top Product
    Discover our top product CBS Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 551 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Yamane, Kanno, Nakamura, Fujino, Murayama: "Hydrogen sulfide-mediated regulation of contractility in the mouse ileum with electrical stimulation: roles of L-cysteine, cystathionine β-synthase, and K+ channels." dans: European journal of pharmacology, Vol. 740, pp. 112-20, (2014) (PubMed).

    Geillinger, Rathmann, Köhrle, Fiamoncini, Daniel, Kipp: "Hepatic metabolite profiles in mice with a suboptimal selenium status." dans: The Journal of nutritional biochemistry, Vol. 25, Issue 9, pp. 914-22, (2014) (PubMed).

    Porteus, Abdallah, Pollack, Kumai, Kwong, Yew, Milsom, Perry: "The role of hydrogen sulphide in the control of breathing in hypoxic zebrafish (Danio rerio)." dans: The Journal of physiology, Vol. 592, Issue 14, pp. 3075-88, (2014) (PubMed).

    Dahlhoff, Worsch, Sailer, Hummel, Fiamoncini, Uebel, Obeid, Scherling, Geisel, Bader, Daniel: "Methyl-donor supplementation in obese mice prevents the progression of NAFLD, activates AMPK and decreases acyl-carnitine levels." dans: Molecular metabolism, Vol. 3, Issue 5, pp. 565-80, (2014) (PubMed).

    Fernandes, Ribeiro, Martínez, Orensanz, Barahona, Martínez-Sáenz, Recio, Benedito, Bustamante, Carballido, García-Sacristán, Prieto, Hernández: "Endogenous hydrogen sulfide has a powerful role in inhibitory neurotransmission to the pig bladder neck." dans: The Journal of urology, Vol. 189, Issue 4, pp. 1567-73, (2013) (PubMed).

    Markand, Tawfik, Ha, Gnana-Prakasam, Sonne, Ganapathy, Sen, Xian, Smith: "Cystathionine beta synthase expression in mouse retina." dans: Current eye research, Vol. 38, Issue 5, pp. 597-604, (2013) (PubMed).

    Dahlhoff, Desmarchelier, Sailer, Fürst, Haag, Ulbrich, Hummel, Obeid, Geisel, Bader, Daniel: "Hepatic methionine homeostasis is conserved in C57BL/6N mice on high-fat diet despite major changes in hepatic one-carbon metabolism." dans: PLoS ONE, Vol. 8, Issue 3, pp. e57387, (2013) (PubMed).

    Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." dans: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

  • Antigène
    CBS (Cystathionine-beta-Synthase (CBS))
    Autre désignation
    CBS (CBS Produits)
    Synonymes
    anticorps hip4, anticorps GB12529, anticorps CBS, anticorps DDBDRAFT_0189727, anticorps DDBDRAFT_0191292, anticorps DDB_0189727, anticorps DDB_0191292, anticorps cbs, anticorps AI047524, anticorps AI303044, anticorps HIP4, anticorps cb442, anticorps wu:fb37g05, anticorps wu:fm61c07, anticorps wu:fq06c06, anticorps zgc:113704, anticorps cystathionine-beta-synthase L homeolog, anticorps cystathionine-beta-synthase, anticorps cystathionine beta-synthase, anticorps cystathionine beta-synthase CBS, anticorps cystathionine beta synthase, anticorps cystathionine-beta-synthase S homeolog, anticorps cystathionine-beta-synthase b, anticorps cbs.L, anticorps cbs, anticorps Cbs, anticorps CBS, anticorps CNA06170, anticorps Tb11.02.5400, anticorps cysB, anticorps LOC100635325, anticorps cbs.S, anticorps cbsb
    Sujet
    CBS is involved in the transsulfuration pathway. The first step of this pathway, from homocysteine to cystathionine, is catalyzed by this protein. CBS deficiency can cause homocystinuria which affects many organs and tissues, including the eyes and the skeletal, vascular and central nervous systems.The protein encoded by this gene is involved in the transsulfuration pathway. The first step of this pathway, from homocysteine to cystathionine, is catalyzed by this protein. CBS deficiency can cause homocystinuria which affects many organs and tissues, including the eyes and the skeletal, vascular and central nervous systems.
    Alias Symbols: HIP4
    Protein Interaction Partner: UBASH3A, UBE2I, PSMA1, PRKAG1, PIN1, EHHADH, CBS, SUMO1, UBC, NEDD8, PIAS3, RANBP9, PIAS1, CBX4, SRP14, RAD23B, PKM, NUCB1, IREB2, HSF1, LRSAM1, C14orf142, UBA5, IPO4, GOPC, PARP6, NPLOC4, DERA, ERO1L, DBNL, GPN1, PDLIM5, PLIN3, UBA2, GPSM1, COL4A3BP, UGP
    Protein Size: 551
    Poids moléculaire
    60 kDa
    ID gène
    875
    NCBI Accession
    NM_000071, NP_000062
    UniProt
    P35520
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