RRM2 anticorps (N-Term)
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- Antigène Voir toutes RRM2 Anticorps
- RRM2 (Ribonucleotide Reductase M2 (RRM2))
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Épitope
- N-Term
- Reactivité
- Humain, Rat, Cobaye, Cheval, Boeuf (Vache), Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RRM2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- PALSGTRVLA SKTARRIFQE PTEPKTKAAA PGVEDEPLLR ENPRRFVIFP
- Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against RRM2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human RRM2
- Top Product
- Discover our top product RRM2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 389 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins." dans: PLoS ONE, Vol. 8, Issue 3, pp. e58456, (2013) (PubMed).
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Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins." dans: PLoS ONE, Vol. 8, Issue 3, pp. e58456, (2013) (PubMed).
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- Antigène
- RRM2 (Ribonucleotide Reductase M2 (RRM2))
- Autre désignation
- RRM2 (RRM2 Produits)
- Synonymes
- anticorps R2, anticorps RR2, anticorps RR2M, anticorps AA407299, anticorps rrm2, anticorps rr2m, anticorps cb111, anticorps chunp6884, anticorps r2, anticorps ribonucleotide reductase regulatory subunit M2, anticorps ribonucleotide reductase M2, anticorps ribonucleotide reductase M2, gene 2 L homeolog, anticorps ribonucleotide reductase M2, gene 1, anticorps ribonucleotide reductase M2 polypeptide, anticorps RRM2, anticorps Rrm2, anticorps rrm2.2.L, anticorps rrm2.1, anticorps rrm2
- Sujet
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RRM2 provides the precursors necessary for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. RRM2 inhibits Wnt signaling.Ribonucleotide reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. It is composed of 2 non-identical subunits, proteins M1 and M2. Synthesis of M2 is regulated in a cell-cycle dependent fashion. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: R2, RR2M, RR2
Protein Interaction Partner: DNM1L, UBC, gag-pol, RBMX, PCMT1, NONO, UBD, SKP2, NR1H4, RRM1, CCNF, ELAVL1, KAT5, RRM2B, CDH1, TP53, CDK1,
Protein Size: 389 - Poids moléculaire
- 45 kDa
- ID gène
- 6241
- NCBI Accession
- NM_001034, NP_001025
- UniProt
- P31350
- Pathways
- Mitotic G1-G1/S Phases
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