CTH anticorps (C-Term)

N° du produit ABIN2782464

Détail du produit anti-CTH anticorps

Antigène: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTH est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: ESNPWVEKVI YPGLPSHPQH ELVKRQCTGC TGMVTFYIKG TLQHAEIFLK

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against CTH. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CTH

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 405 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CTH (ABIN2782464)

Fernandes, Ribeiro, Martínez, Orensanz, Barahona, Martínez-Sáenz, Recio, Benedito, Bustamante, Carballido, García-Sacristán, Prieto, Hernández: "Endogenous hydrogen sulfide has a powerful role in inhibitory neurotransmission to the pig bladder neck." dans: The Journal of urology, Vol. 189, Issue 4, pp. 1567-73, (2013) (PubMed).

Détails sur CTH

Antigène: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Autre désignation: CTH (CTH Produits)

Synonymes: anticorps DYT17, anticorps DYT18, anticorps DYT9, anticorps EIG12, anticorps GLUT, anticorps GLUT1, anticorps GLUT1DS, anticorps HTLVR, anticorps PED, anticorps wu:fb48e03, anticorps wu:fb58d08, anticorps zgc:66001, anticorps zgc:85785, anticorps CTH, anticorps 0610010I13Rik, anticorps AI314617, anticorps BC019483, anticorps CSE, anticorps Cys3, anticorps cysA, anticorps SCQ11.03c, anticorps DDBDRAFT_0190313, anticorps DDBDRAFT_0191318, anticorps DDB_0190313, anticorps DDB_0191318, anticorps H, anticorps MGC75946, anticorps cystathionine gamma-lyase, anticorps solute carrier family 2 member 1, anticorps cystathionase (cystathionine gamma-lyase), anticorps cystathionine gamma-lyase L homeolog, anticorps CTH, anticorps SLC2A1, anticorps cth, anticorps Cth, anticorps SCO3920, anticorps mlr1566, anticorps TA_RS00415, anticorps MAP_RS15640, anticorps SPO3344, anticorps CNN01730, anticorps Mmcs_1928, anticorps RHA1_RS31820, anticorps HNE_1212, anticorps MAV_3867, anticorps MSMEG_2394, anticorps Mvan_2142, anticorps SACE_6136, anticorps Mflv_4220, anticorps cysA, anticorps cth.L

Sujet: CTH is a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in its gene cause cystathioninuria.This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Alias Symbols: MGC9471
Protein Interaction Partner: GUCD1, WDYHV1, RECK, CTH, PTMA, GMDS, CAPN2, ATIC, SDCBP2, UBC, ELAVL1,
Protein Size: 405

Poids moléculaire: 44 kDa

ID gène: 1491

NCBI Accession: NM_001902, NP_001893

UniProt: P32929

Pathways: ER-Nucleus Signaling, L'effet Warburg