PDK3 anticorps (N-Term)

N° du produit ABIN2782501

Détail du produit anti-PDK3 anticorps

Antigène: PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio), Chien, Cheval, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDK3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: RPSVGLVQSW YMQSFLELLE YENKSPEDPQ VLDNFLQVLI KVRNRHNDVV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 75%

Attributs du produit: This is a rabbit polyclonal antibody against PDK3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PDK3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 406 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PDK3

Antigène: PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

Autre désignation: PDK3 (PDK3 Produits)

Synonymes: anticorps pdk3, anticorps PDK3, anticorps 2610001M10Rik, anticorps AI035637, anticorps zgc:158702, anticorps pyruvate dehydrogenase kinase 3, anticorps pyruvate dehydrogenase kinase, isozyme 3a, anticorps pyruvate dehydrogenase kinase, isoenzyme 3, anticorps fragile site, 5-azacytidine type, common, fra(1)(q12), anticorps pyruvate dehydrogenase kinase, isozyme 3b, anticorps PDK3, anticorps Pdk3, anticorps pdk3a, anticorps pdk3, anticorps FRA1J, anticorps pdk3b

Sujet: PDK3 belongs to the PDK/BCKDK protein kinase family. It contains 1 histidine kinase domain. PDK3 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Alias Symbols: -
Protein Interaction Partner: APP, UBD, UBC, ICT1, EGFR, DLAT, PDHA1,
Protein Size: 406

Poids moléculaire: 47 kDa

ID gène: 5165

NCBI Accession: NM_005391, NP_005382

UniProt: Q15120

Pathways: Signalisation PI3K-Akt, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg