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PFAS anticorps (N-Term)

PFAS Reactivité: Humain, Souris, Boeuf (Vache), Cobaye, Cheval, Lapin WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2782529
  • Antigène Voir toutes PFAS Anticorps
    PFAS (Phosphoribosylformylglycinamidine Synthase (PFAS))
    Épitope
    • 8
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Souris, Boeuf (Vache), Cobaye, Cheval, Lapin
    Hôte
    • 32
    Lapin
    Clonalité
    • 32
    Polyclonal
    Conjugué
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PFAS est non-conjugé
    Application
    • 20
    • 17
    • 15
    • 13
    • 3
    • 1
    Western Blotting (WB)
    Séquence
    ESIMSTQESS NPNNVLKFCD NSSAIQGKEV RFLRPEDPTR PSRFQQQQGL
    Homologie
    Cow: 83%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 79%
    Attributs du produit
    This is a rabbit polyclonal antibody against PFAS. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human PFAS
    Top Product
    Discover our top product PFAS Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 1338 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • French, Zhao, An, Niessen, Deng, Cravatt, Benkovic: "Hsp70/Hsp90 chaperone machinery is involved in the assembly of the purinosome." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 7, pp. 2528-33, (2013) (PubMed).

    Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • Antigène
    PFAS (Phosphoribosylformylglycinamidine Synthase (PFAS))
    Autre désignation
    PFAS (PFAS Produits)
    Synonymes
    anticorps FGAMS, anticorps FGARAT, anticorps PURL, anticorps 4432409B16Rik, anticorps Gm18, anticorps Sofa, anticorps phosphoribosylformylglycinamidine synthase, anticorps phosphoribosylformylglycinamidine synthase (FGAR amidotransferase), anticorps Spirs_3128, anticorps PFAS, anticorps Pfas
    Sujet
    Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. PFAS catalyzes the fourth step of IMP biosynthesis. Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis.
    Alias Symbols: FGAMS, FGARAT, KIAA0361, PURL
    Protein Interaction Partner: UBC, SUMO2, TNRC6B, GINS3, ISOC1, BZW2, DCPS, MAT2B, ABHD14A, ERP44, PDCD10, FERMT2, NPEPPS, CNBP, YWHAZ, VCL, RAP1GDS1, PAK2, MSN, LDHB, HSPA9, EIF5, EEF2, ECHS1, DFFA, CKB, CAPN1, SGTA, XIAP, UBR1, USP28, PPP6R3, ZNF593, SEPHS1, CHERP, PRDX6, USP14, UBD
    Protein Size: 1338
    Poids moléculaire
    145 kDa
    ID gène
    5198
    NCBI Accession
    NM_012393, NP_036525
    UniProt
    O15067
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