SWAP70 anticorps (N-Term)

N° du produit ABIN2782542

Détail du produit anti-SWAP70 anticorps

Antigène: SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SWAP70 est non-conjugé

Application: Western Blotting (WB)

Séquence: ALEEHFRDDD EGPVSNQGYM PYLNRFILEK VQDNFDKIEF NRMCWTLCVK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SWAP70. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SWAP70

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 585 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SWAP70 (ABIN2782542)

Rosati, Krebs, Liu: "Emissions from cooking microwave popcorn." dans: Critical reviews in food science and nutrition, Vol. 47, Issue 8, pp. 701-9, (2007) (PubMed).

Détails sur SWAP70

Antigène: SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Autre désignation: SWAP70 (SWAP70 Produits)

Synonymes: anticorps SWAP-70, anticorps 70kDa, anticorps AV235546, anticorps HSPC321, anticorps swap70b, anticorps zgc:63599, anticorps switching B-cell complex subunit SWAP70, anticorps SWA-70 protein, anticorps SWAP switching B-cell complex 70, anticorps SWAP switching B-cell complex 70kDa subunit, anticorps switching B-cell complex subunit SWAP70a, anticorps SWAP70, anticorps Swap70, anticorps swap70, anticorps swap70a

Sujet: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. SWAP70 also mediates signaling of membrane ruffling. It regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
Alias Symbols: FLJ39540, HSPC321, KIAA0640, SWAP-70
Protein Interaction Partner: ZBTB5, RAPGEF4, UBC, CORO1B, ASUN, OTUD6B, JMJD6, GANAB, PACSIN2, FAF1, PAICS, FARSB, ZRANB2, RANBP3, CUL1, SUPT5H, SET, PPP2R5C, PLOD2, OSBP, GART, XRCC6, CRMP1, ATP6V1B2, C18orf8, CELSR3, IGHG1, PARP1, NPM1, NCL,
Protein Size: 585

Poids moléculaire: 69 kDa

ID gène: 23075

NCBI Accession: NM_015055, NP_055870

UniProt: Q9UH65

Pathways: Production of Molecular Mediator of Immune Response