DLL1 anticorps (N-Term)

N° du produit ABIN2782684

Détail du produit anti-DLL1 anticorps

Antigène: DLL1 (delta-Like 1 (DLL1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: GSRCALALAV LSALLCQVWS SGVFELKLQE FVNKKGLLGN RNCCRGGAGP

Homologie: Cow: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against DLL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DLL1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 723 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-DLL1 (ABIN2782684)

Caliceti, Aquila, Pannella, Morelli, Fortini, Pinton, Bonora, Hrelia, Pannuti, Miele, Rizzo, Ferrari: "17?-estradiol enhances signalling mediated by VEGF-A-delta-like ligand 4-notch1 axis in human endothelial cells." dans: PLoS ONE, Vol. 8, Issue 8, pp. e71440, (2013) (PubMed).

Suprynowicz, Upadhyay, Krawczyk, Kramer, Hebert, Liu, Yuan, Cheluvaraju, Clapp, Boucher, Kamonjoh, Randell, Schlegel: "Conditionally reprogrammed cells represent a stem-like state of adult epithelial cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 49, pp. 20035-40, (2012) (PubMed).

Détails sur DLL1

Antigène: DLL1 (delta-Like 1 (DLL1))

Autre désignation: DLL1 (DLL1 Produits)

Synonymes: anticorps X-delta-1, anticorps XDelta1, anticorps Xdelta-1, anticorps delta, anticorps delta-1, anticorps delta1, anticorps x-delta, anticorps DELTA1, anticorps DL1, anticorps Delta, anticorps DLK, anticorps DLK-1, anticorps Delta1, anticorps FA1, anticorps PREF1, anticorps Pref-1, anticorps ZOG, anticorps pG2, anticorps DLL1, anticorps AW742678, anticorps DlkI, anticorps Ly107, anticorps Peg9, anticorps SCP1, anticorps pref-1, anticorps delta-like 1, anticorps delta like canonical Notch ligand 1, anticorps delta like non-canonical Notch ligand 1, anticorps delta-like 1 L homeolog, anticorps delta-like 1 (Drosophila), anticorps delta-like 1 homolog (Drosophila), anticorps dll1, anticorps DLL1, anticorps DLK1, anticorps Dll1, anticorps dll1.L, anticorps Dlk1

Sujet: DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication.DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DELTA1, Delta, DL1
Protein Interaction Partner: EPN1, UBC, MIB1, MAGI2, CNKSR3, POFUT1, DLL1, MFNG, ADAM10, NOTCH3, NOTCH2, NOTCH1, NOV, PSEN1, MAGI1,
Protein Size: 723

Poids moléculaire: 78 kDa

ID gène: 28514

NCBI Accession: NM_005618, NP_005609

UniProt: O00548

Pathways: Signalisation Notch, Stem Cell Maintenance