ZMPSTE24 anticorps (N-Term)
-
- Antigène Voir toutes ZMPSTE24 (Zmpste24) Anticorps
- ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))
-
Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien, Cobaye, Poisson zèbre (Danio rerio)
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp ZMPSTE24 est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- LYSETEGTLI LLFGGIPYLW RLSGRFCGYA GFGPEYEITQ SLVFLLLATL
- Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 91%, Zebrafish: 90%
- Attributs du produit
- This is a rabbit polyclonal antibody against ZMPSTE24. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human ZMPSTE24
- Top Product
- Discover our top product Zmpste24 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 475 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))
- Autre désignation
- ZMPSTE24 (Zmpste24 Produits)
- Synonymes
- anticorps DDBDRAFT_0189115, anticorps DDBDRAFT_0237846, anticorps DDB_0189115, anticorps DDB_0237846, anticorps F2N1.21, anticorps F2N1_21, anticorps STE24, anticorps FACE-1, anticorps FACE1, anticorps HGPS, anticorps PRO1, anticorps Ste24p, anticorps A530043O15Rik, anticorps D030046F19, anticorps Face-1, anticorps MADB, anticorps fi45a02, anticorps wu:fi45a02, anticorps zgc:55655, anticorps zinc metallopeptidase STE24, anticorps zinc metallopeptidase STE24 L homeolog, anticorps CAAX prenyl protease, anticorps Peptidase family M48 family protein, anticorps zinc metallopeptidase, STE24, anticorps zinc metallopeptidase, STE24 homolog, anticorps ZMPSTE24, anticorps zmpste24.L, anticorps zmpste24, anticorps ATSTE24, anticorps Zmpste24
- Sujet
-
ZMPSTE24 is a member of the peptidase M48A family. This protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in ZMPSTE24 gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.The protein encoded by this gene is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.
Alias Symbols: FACE-1, FACE1, FLJ14968, STE24, Ste24p, HGPS, PRO1
Protein Interaction Partner: UBC, BAG3, KIAA2013, TMEM43, MRPL40, MRPS5, SYNJ2BP, ATP6V1H, HNRNPUL1, RAB10, VDAC1, UQCRFS1P1, S100A10, RAB5C, PTPN1, NDUFB7, MGST3, HNRNPF, GALNT2, DDOST, CD55, ELAVL1, MME,
Protein Size: 475 - Poids moléculaire
- 55 kDa
- ID gène
- 10269
- NCBI Accession
- NM_005857, NP_005848
- UniProt
- O75844
-