BMP10 anticorps (C-Term)
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- Antigène Voir toutes BMP10 Anticorps
- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Lapin, Chien, Cheval, Boeuf (Vache), Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BMP10 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GYEAYECRGV CNYPLAEHLT PTKHAIIQAL VHLKNSQKAS KACCVPTKLE
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against BMP10. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human BMP10
- Top Product
- Discover our top product BMP10 Anticorps primaire
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
- Autre désignation
- BMP10 (BMP10 Produits)
- Synonymes
- anticorps BMP10, anticorps si:dkey-13n15.5, anticorps Bmp10, anticorps BMP9, anticorps BMP-10, anticorps bone morphogenetic protein 10, anticorps BMP10, anticorps bmp10, anticorps LOC662386, anticorps Bmp10
- Sujet
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BMP10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. It acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth.
Alias Symbols: -
Protein Interaction Partner: BMPR2, ACVR2B, ACVR2A, SERINC3,
Protein Size: 424 - Poids moléculaire
- 46 kDa
- ID gène
- 27302
- NCBI Accession
- NM_014482, NP_055297
- UniProt
- O95393
- Pathways
- Hormone Activity, Regulation of Muscle Cell Differentiation
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