EDEM1 anticorps (N-Term)

N° du produit ABIN2782826

Détail du produit anti-EDEM1 anticorps

Antigène: EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))

Épitope: N-Term

Reactivité: Humain, Souris, Lapin, Boeuf (Vache), Rat, Cobaye, Chien, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EDEM1 est non-conjugé

Application: Western Blotting (WB)

Séquence: MAHAFPQDEL NPIHCRGRGP DRGDPSNLNI NDVLGNYSLT LVDALDTLAI

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%

Attributs du produit: This is a rabbit polyclonal antibody against EDEM1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human EDEM1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 657 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur EDEM1

Antigène: EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))

Autre désignation: EDEM1 (EDEM1 Produits)

Synonymes: anticorps zgc:55816, anticorps edem, anticorps EDEM1, anticorps EDEM, anticorps A130059K23Rik, anticorps mKIAA0212, anticorps RGD1563633, anticorps ER degradation enhancer, mannosidase alpha-like 1, anticorps ER degradation enhancing alpha-mannosidase like protein 1, anticorps ER degradation-enhancing alpha-mannosidase-like protein 1, anticorps ER degradation enhancing alpha-mannosidase like protein 1 L homeolog, anticorps edem1, anticorps EDEM1, anticorps LOC100637820, anticorps edem1.L, anticorps Edem1

Sujet: EDEM1 belongs to the glycosyl hydrolase 47 family. It extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner.
Alias Symbols: EDEM, KIAA0212
Protein Interaction Partner: HLA-B, SQSTM1, UBC, MMS19, SSR1, ASGR1, DERL1, DNAJC10, DERL2, SEC61B, SEL1L, RHO, CANX, RCOM_2159910, ASGR2, ELAVL1, BZW1,
Protein Size: 657

Poids moléculaire: 74 kDa

ID gène: 9695

NCBI Accession: NM_014674, NP_055489

UniProt: Q92611

Pathways: ER-Nucleus Signaling