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COQ2 anticorps (Middle Region)

COQ2 Reactivité: Humain, Souris, Rat, Porc, Lapin, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio), Chien, Chévre, Cheval WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2782857
  • Antigène Voir toutes COQ2 Anticorps
    COQ2 (Coenzyme Q2 Homolog, Prenyltransferase (COQ2))
    Épitope
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    Humain, Souris, Rat, Porc, Lapin, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio), Chien, Chévre, Cheval
    Hôte
    • 3
    • 2
    Lapin
    Clonalité
    • 3
    • 2
    Polyclonal
    Conjugué
    • 5
    Cet anticorp COQ2 est non-conjugé
    Application
    • 4
    • 3
    Western Blotting (WB)
    Séquence
    FSGVMWTLIY DTIYAHQDKR DDVLIGLKST ALRFGENTKP WLSGFSVAML
    Homologie
    Dog: 93%, Goat: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 93%, Rat: 86%, Yeast: 91%, Zebrafish: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against COQ2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human COQ2
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 384 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Sasaki, Kotoh, Watadani, Matsumoto: "New animal models reveal that coenzyme Q2 (Coq2) and placenta-specific 8 (Plac8) are candidate genes for the onset of type 2 diabetes associated with obesity in rats." dans: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 26, Issue 11-12, pp. 619-29, (2015) (PubMed).

  • Antigène
    COQ2 (Coenzyme Q2 Homolog, Prenyltransferase (COQ2))
    Autre désignation
    COQ2 (COQ2 Produits)
    Synonymes
    anticorps CG9613, anticorps COQ2, anticorps Dmel\\CG9613, anticorps coq2, anticorps sbo, anticorps CL640, anticorps COQ10D1, anticorps MSA1, anticorps RGD1306722, anticorps zgc:162600, anticorps 2310002F18Rik, anticorps Coenzyme Q biosynthesis protein 2, anticorps coenzyme Q2, polyprenyltransferase, anticorps coenzyme Q2 4-hydroxybenzoate polyprenyltransferase, anticorps 4-hydroxybenzoate polyprenyltransferase, mitochondrial, anticorps Coq2, anticorps COQ2, anticorps coq2, anticorps coq-2
    Sujet
    COQ2 catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. COQ2 mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB.CoQ (ubiquinone) serves as a redox carrier in the mitochondrial respiratory chain and is a lipid-soluble antioxidant. COQ2, or parahydroxybenzoate-polyprenyltransferase (EC 2.5.1.39), catalyzes one of the final reactions in the biosynthesis of CoQ, the prenylation of parahydroxybenzoate with an all-trans polyprenyl group (Forsgren et al., 2004 [PubMed 15153069]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-90 BC020728.1 1-90 91-96 BG699931.1 80-85 97-789 BC020728.1 97-789 790-792 BQ363759.1 169-171 793-1535 BC020728.1 793-1535 1536-1554 BC008804.2 1496-1514
    Alias Symbols: CL640, FLJ26072
    Protein Interaction Partner: UBC,
    Protein Size: 384
    Poids moléculaire
    42 kDa
    ID gène
    27235
    NCBI Accession
    NM_015697, NP_056512
    UniProt
    Q96H96
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