Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

NAGPA anticorps (N-Term)

NAGPA Reactivité: Humain, Boeuf (Vache), Chien, Cobaye, Cheval, Souris, Rat, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2782884
  • Antigène Voir toutes NAGPA Anticorps
    NAGPA (N-Acetylglucosamine-1-phosphodiester alpha-N-Acetylglucosaminidase (NAGPA))
    Épitope
    • 4
    • 1
    • 1
    N-Term
    Reactivité
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Boeuf (Vache), Chien, Cobaye, Cheval, Souris, Rat, Poisson zèbre (Danio rerio)
    Hôte
    • 5
    • 1
    Lapin
    Clonalité
    • 6
    Polyclonal
    Conjugué
    • 3
    • 1
    • 1
    • 1
    Cet anticorp NAGPA est non-conjugé
    Application
    • 4
    • 3
    • 1
    Western Blotting (WB)
    Séquence
    GECLGNVVSD ERRVSSSGGL QNAQFGIRRD GTLVTGYLSE EEVLDTENPF
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against NAGPA. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human NAGPA
    Top Product
    Discover our top product NAGPA Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeat freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    NAGPA (N-Acetylglucosamine-1-phosphodiester alpha-N-Acetylglucosaminidase (NAGPA))
    Autre désignation
    NAGPA (NAGPA Produits)
    Synonymes
    anticorps NAGPA, anticorps APAA, anticorps UCE, anticorps AI596180, anticorps N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, anticorps NAGPA, anticorps NAEGRDRAFT_56913, anticorps Nagpa
    Sujet
    Hydrolases are transported to lysosomes after binding to mannose 6-phosphate receptors in the trans-Golgi network. This gene encodes the enzyme that catalyzes the second step in the formation of the mannose 6-phosphate recognition marker on lysosomal hydrolases. Commonly known as 'uncovering enzyme' or UCE, this enzyme removes N-acetyl-D-glucosamine (GlcNAc) residues from GlcNAc-alpha-P-mannose moieties and thereby produces the recognition marker. This reaction most likely occurs in the trans-Golgi network. This enzyme functions as a homotetramer of two disulfide-linked homodimers. In addition to having an N-terminal signal peptide, the protein's C-terminus contains multiple signals for trafficking it between lysosomes, the plasma membrane, and trans-Golgi network.
    Alias Symbols: APAA, UCE
    Protein Interaction Partner: ZHX2, DEGS1, NAGPA, EPS15, AP2A1, FURIN,
    Protein Size: 515
    Poids moléculaire
    53 kDa
    ID gène
    51172
    NCBI Accession
    NM_016256, NP_057340
    UniProt
    Q9UK23
Vous êtes ici:
Support technique