CLN6 anticorps (C-Term)
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- Antigène Voir toutes CLN6 Anticorps
- CLN6 (Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Chien, Cheval, Cobaye, Lapin, Boeuf (Vache), Mouton, Poisson zèbre (Danio rerio), Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CLN6 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- RLFLDSNGLF LFSSFALTLL LVALWVAWLW NDPVLRKKYP GVIYVPEPWA
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against CLN6. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human CLN6
- Top Product
- Discover our top product CLN6 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 311 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CLN6 (Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6))
- Autre désignation
- CLN6 (CLN6 Produits)
- Synonymes
- anticorps 1810065L06Rik, anticorps AW743417, anticorps D9Bwg1455e, anticorps nclf, anticorps CLN4A, anticorps HsT18960, anticorps cln6, anticorps zgc:103565, anticorps ceroid-lipofuscinosis, neuronal 6, anticorps CLN6, transmembrane ER protein, anticorps CLN6, transmembrane ER protein S homeolog, anticorps ceroid-lipofuscinosis, neuronal 6, late infantile, variant, anticorps CLN6, transmembrane ER protein a, anticorps Cln6, anticorps CLN6, anticorps cln6.S, anticorps cln6a
- Sujet
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CLN6 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely CLN6 involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.
Alias Symbols: FLJ20561, HsT18960, nclf, CLN4A
Protein Interaction Partner: RNF2, BMI1, ILK, env, DERL1, VCP, UBC,
Protein Size: 311 - Poids moléculaire
- 36 kDa
- ID gène
- 54982
- NCBI Accession
- NM_017882, NP_060352
- UniProt
- Q9NWW5
- Pathways
- Glycosaminoglycan Metabolic Process
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