ADCY10 anticorps (N-Term)

N° du produit ABIN2782970

Détail du produit anti-ADCY10 anticorps

Antigène: ADCY10 (Adenylate Cyclase 10 (Soluble) (ADCY10))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADCY10 est non-conjugé

Application: Western Blotting (WB)

Séquence: VGHTVRHEYT VIGQKVNLAA RMMMYYPGIV TCDSVTYNGS NLPAYFFKEL

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SAC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SAC

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1610 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ADCY10 (ABIN2782970)

Corredor, Trakhtenberg, Pita-Thomas, Jin, Hu, Goldberg: "Soluble adenylyl cyclase activity is necessary for retinal ganglion cell survival and axon growth." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 22, pp. 7734-44, (2012) (PubMed).

Détails sur ADCY10

Antigène: ADCY10 (Adenylate Cyclase 10 (Soluble) (ADCY10))

Autre désignation: SAC (ADCY10 Produits)

Synonymes: anticorps HCA2, anticorps RP1-313L4.2, anticorps SAC, anticorps SACI, anticorps Sacy, anticorps Sac, anticorps 4930431D04Rik, anticorps 4931412F17, anticorps sAC, anticorps ADCY10, anticorps SACY, anticorps adenylate cyclase 10, anticorps adenylate cyclase 10 (soluble), anticorps ADCY10, anticorps Adcy10

Sujet: SAC belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction.The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HCA2, RP1-313L4.2, SACI, SAC, Sacy
Protein Interaction Partner: PTGIR, SSTR5,
Protein Size: 1610

Poids moléculaire: 187 kDa

ID gène: 55811

NCBI Accession: NM_018417, NP_060887

UniProt: Q96PN6

Pathways: cAMP Metabolic Process