SMC3 anticorps (N-Term)

N° du produit ABIN2783036

Détail du produit anti-SMC3 anticorps

Antigène: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cheval, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMC3 est non-conjugé

Application: Western Blotting (WB)

Séquence: KWDKMRRALE YTIYNQELNE TRAKLDELSA KRETSGEKSR QLRDAQQDAR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against SMC3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SMC3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1217 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SMC3

Antigène: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Autre désignation: SMC3 (SMC3 Produits)

Synonymes: anticorps cspg6, anticorps xsmc3, anticorps BAM, anticorps BMH, anticorps CDLS3, anticorps CSPG6, anticorps HCAP, anticorps SMC3L1, anticorps Bamacan, anticorps Cspg6, anticorps Mmip1, anticorps SMC-3, anticorps SmcD, anticorps im:7142991, anticorps wu:fb22e01, anticorps wu:fc30d07, anticorps bamacan, anticorps structural maintenance of chromosomes 3, anticorps structural maintenance of chromosomes 3 S homeolog, anticorps smc3, anticorps SMC3, anticorps Smc3, anticorps smc3.S

Sujet: SMC3 belongs to the SMC3 subfamily of SMC proteins. SMC3 occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation.
Alias Symbols: BAM, BMH, CDLS3, CSPG6, HCAP, SMC3L1
Protein Interaction Partner: SUMO2, UBC, RPA3, RPA2, RPA1, SUZ12, EED, RNF2, FBXO6, ANKRD28, HDAC11, HDAC8, HDAC9, SOX2, RAD21, CDCA5, PDS5A, WAPAL, MMS19, METTL21B, NOTCH1, SMC1A, SFPQ, HNRNPM, NSMCE2, UBD, COPS5, COPS6, CUL2, CUL3, NEDD8, CDK2, FBXO25, MECP2, NIPBL, CDK8, SUPT5H, P
Protein Size: 1217

Poids moléculaire: 141 kDa

ID gène: 9126

NCBI Accession: NM_005445, NP_005436

UniProt: Q9UQE7

Pathways: Stem Cell Maintenance