PSMC3IP anticorps (Middle Region)
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- Antigène Voir toutes PSMC3IP Anticorps
- PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))
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Épitope
- Middle Region
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Reactivité
- Souris, Humain, Rat, Chien, Boeuf (Vache), Lapin, Cheval, Chévre, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PSMC3IP est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- RLKNIKAATN HVTPEEKEQV YRERQKYCKE WRKRKRMATE LSDAILEGYP
- Homologie
- Cow: 93%, Dog: 100%, Goat: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against PSMC3IP. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human PSMC3IP
- Top Product
- Discover our top product PSMC3IP Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 217 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))
- Autre désignation
- PSMC3IP (PSMC3IP Produits)
- Synonymes
- anticorps PSMC3IP, anticorps Arabidopsis Hop2 homolog, anticorps T6J4.9, anticorps T6J4_9, anticorps C79099, anticorps GT198, anticorps HOP2, anticorps Tbpip, anticorps HUMGT198A, anticorps ODG3, anticorps TBPIP, anticorps Gt198, anticorps zgc:86785, anticorps PSMC3 interacting protein, anticorps homologous-pairing protein 2 homolog, anticorps Homologous-pairing protein 2 homolog, anticorps homologous-pairing protein 2 homolog-like, anticorps Tat-binding protein 1(Tbp-1)-interacting protein (TBPIP), anticorps proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein, anticorps PSMC3 interacting protein L homeolog, anticorps PSMC3IP, anticorps LOC726449, anticorps LOC100165513, anticorps hop2, anticorps psmc3ip, anticorps LOC100633854, anticorps LOC100650062, anticorps LOC789362, anticorps AHP2, anticorps Psmc3ip, anticorps psmc3ip.L
- Sujet
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PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.
Alias Symbols: GT198, HOP2, TBPIP, ODG3, HUMGT198A
Protein Interaction Partner: PSMC3, PSMC3IP, THRB, ESR2, AR, RXRA, NR3C1,
Protein Size: 217 - Poids moléculaire
- 25 kDa
- ID gène
- 29893
- NCBI Accession
- NM_016556, NP_057640
- UniProt
- Q9P2W1
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