SETD2 anticorps (N-Term)

N° du produit ABIN2783051

Détail du produit anti-SETD2 anticorps

Antigène: SETD2 (SET Domain Containing 2 (SETD2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SETD2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: SDEDSVRTSS SQRSHDLKFS ASIEKERDFK KSSAPLKSED LGKPSRSKTD

Réactivité croisée: Chien, Humain, Rat (Rattus)

Homologie: Cow: 79%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 83%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against SETD2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SETD2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 891 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SETD2 (ABIN2783051)

Barrand, Andersen, Collas: "Promoter-exon relationship of H3 lysine 9, 27, 36 and 79 methylation on pluripotency-associated genes." dans: Biochemical and biophysical research communications, Vol. 401, Issue 4, pp. 611-7, (2010) (PubMed).

Détails sur SETD2

Antigène: SETD2 (SET Domain Containing 2 (SETD2))

Autre désignation: SETD2 / HIF1 (SETD2 Produits)

Synonymes: anticorps Kif9, anticorps HBP231, anticorps HIF-1, anticorps HIP-1, anticorps HYPB, anticorps KMT3A, anticorps SET2, anticorps p231HBP, anticorps SET domain containing 2, anticorps Setd2, anticorps SETD2

Sujet: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. SETD2 is a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs.
Alias Symbols: FLJ16420, FLJ22472, FLJ23184, FLJ45883, HIF-1, HSPC069, HYPB, KIAA1732, KMT3A, SET2, HIP-1, HBP231, p231HBP
Protein Interaction Partner: CLK2, SOX2, CBX8, HCVgp1, SIAH2, SMAD3, CIC, ATXN1, ELAVL1, UBC, SETD2, HIST1H3A, POLR2A, TP53, IWS1, HTT,
Protein Size: 891

Poids moléculaire: 97 kDa

ID gène: 29072

NCBI Accession: NM_014159

UniProt: Q9BYW2

Pathways: Tube Formation